Evidence map›Paper›PMID 36515504›Full record

ArticleMicrobiology spectrum2023

Rich Organic Nitrogen Impacts Clavulanic Acid Biosynthesis through the Arginine Metabolic Pathway in Streptomyces clavuligerus F613-1.

Jiafang Fu, Xinru Xie, Shaowei Zhang, Ni Kang, Gongli Zong, Peipei Zhang, Guangxiang Cao

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiafang FuBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Xinru XieBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Shaowei ZhangBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Ni KangBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Gongli ZongBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Peipei ZhangBiomedical Sciences College, Shandong First Medical University, Jinan, China.
Guangxiang CaoBiomedical Sciences College, Shandong First Medical University, Jinan, China.ORCID 0000-0002-0581-7832
Shandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clavulanic acid (CA) is the preferred clinical drug for the treatment of infections by β-lactam antibiotic-resistant bacteria. CA is produced by Streptomyces clavuligerus, and although there have been many reports on the effects of carbon and nitrogen sources on CA production, the mechanisms involved remain unclear. In this study, we found that CA accumulation in

Indexed as

ArginineGlutamineAmino AcidsAnti-Bacterial AgentsClavulanic AcidGlutamatesMetabolic Networks and PathwaysNitrogenStreptomycesAmino AcidsAnti-Bacterial AgentsArginineClavulanic AcidGlutamatesGlutamineNitrogenarginine metabolismclavulanic acidmetabolometranscriptome

Identifiers

PMID36515504
PMCPMC9927107
OpenAlexW4311481014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.