ArticleEuropean journal of public health2023
Defining vulnerability subgroups among pregnant women using pre-pregnancy information: a latent class analysis.
Article in European journal of public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Maternal perinatal vulnerability and its influencing factors in different stages.BMC pregnancy and childbirth · 2026Observational
- A quantitative content analysis of Chinese policies on fertility-friendly hospital development: a three-dimensional framework.Frontiers in public health · 2026Article
- Identifying cardiovascular health profiles in early pregnancy: A "Life's Essential 8"-based approach to assessing risk of hypertensive disorders of pregnancy.Pregnancy hypertension · 2025Observational
- Article
- Preconception Oral Health Is Associated with Modifiable Health Behaviors.Journal of dental research · 2025Article
- Maternal and gestational factors associated with congenital anomalies among live births: a nationwide population-based study in Brazil from 2012 to 2020.BMC pregnancy and childbirth · 2025Article
- Clustering of non-medical risk factors and the association with duration of social care in pregnant women in highly vulnerable circumstances.European journal of public health · 2025Article
- Predicting population-level vulnerability among pregnant women using routinely collected data and the added relevance of self-reported data.European journal of public health · 2024Article
- The extent of implementation and perceptions of maternity and social care professionals about two interprofessional programs for care for pregnant women: a mixed methods study.BMC pregnancy and childbirth · 2024Article
- Computational Approaches for Connecting Maternal Stress to Preterm Birth.Clinics in perinatology · 2024Review
- Multiple Risk in Pregnancy- Prenatal Risk Constellations and Mother-Infant Interactions, Parenting Stress, and Child Externalizing and Internalizing Behaviors: A Prospective Longitudinal Cohort Study from Pregnancy to 18 Months Postpartum.Research on child and adolescent psychopathology · 2024Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
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Abstract
backgroundEarly detection of vulnerability during or before pregnancy can contribute to optimizing the first 1000 days, a crucial period for children's development and health. We aimed to identify classes of vulnerability among pregnant women in the Netherlands using pre-pregnancy data on a wide range of social risk and protective factors, and validate these classes against the risk of adverse outcomes.
methodsWe conducted a latent class analysis based on 42 variables derived from nationwide observational data sources and self-reported data. Variables included individual, socioeconomic, lifestyle, psychosocial and household characteristics, self-reported health, healthcare utilization, life-events and living conditions. We compared classes in relation to adverse outcomes using logistic regression analyses.
resultsIn the study population of 4172 women, we identified five latent classes. The largest 'healthy and socioeconomically stable'-class [n = 2040 (48.9%)] mostly shared protective factors, such as paid work and positively perceived health. The classes 'high care utilization' [n = 485 (11.6%)], 'socioeconomic vulnerability' [n = 395 (9.5%)] and 'psychosocial vulnerability' [n = 1005 (24.0%)] were characterized by risk factors limited to one specific domain and protective factors in others. Women classified into the 'multidimensional vulnerability'-class [n = 250 (6.0%)] shared multiple risk factors in different domains (psychosocial, medical and socioeconomic risk factors). Multidimensional vulnerability was associated with adverse outcomes, such as premature birth and caesarean section.
conclusionsCo-existence of multiple risk factors in various domains is associated with adverse outcomes for mother and child. Early detection of vulnerability and strategies to improve parental health and well-being might benefit from focussing on different domains and combining medical and social care and support.
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