Evidence map›Paper›PMID 36515406›Full record

SynthesisJournal of psychopharmacology (Oxford, England)2023

Therapeutic uses of psychedelics for eating disorders and body dysmorphic disorder.

Nicole Ledwos, Justyne D Rodas, M Ishrat Husain, Jamie D Feusner, David J Castle

Open access · greenAbstract readSystematic ReviewCase Reports
In one paragraph

Synthesis in Journal of psychopharmacology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Nicole LedwosCentre for Complex Interventions, Centre for Addiction and Mental Health, Toronto, ON, Canada.ORCID 0000-0002-8604-3313
Justyne D RodasCentre for Complex Interventions, Centre for Addiction and Mental Health, Toronto, ON, Canada.
M Ishrat HusainCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Jamie D FeusnerInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
David J CastleCentre for Complex Interventions, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Centre for Addiction and Mental Health · CA

Funding

Neural mechanisms of perceptual abnormalities and their malleability in bodydysmorphic disorderR01MH121520 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FEUSNER, JAMIE · 2020 to 2025
$2.8M
Exogenous Modulation of Visual Perception And Connectivity in Body Dysmorphic Disorder (EMPAC-BDD)R21MH128815 · NIMH · CENTRE FOR ADDICTION AND MENTAL HEALTH · PI FEUSNER, JAMIE · 2022 to 2023
$273k
NIMH NIH HHS R01 MH121520NIMH NIH HHS R21 MH128815
6 · The paper itself

Abstract

backgroundClinical use of psychedelics has gained considerable attention, with promising benefits across a range of mental disorders. Current pharmacological and psychotherapeutic treatments for body dysmorphic disorder (BDD) and eating disorders (EDs) have limited efficacy. As such, other treatment options such as psychedelic-assisted therapies are being explored in these clinical groups.

aimsThis systematic review evaluates evidence related to the therapeutic potential of psychedelics in individuals diagnosed with BDD and EDs.

methodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a systematic review of all study designs published to the end of February 2022 that identified changes in ED/BDD symptom severity from psychedelics using validated measures to assess symptom changes.

resultsOur search detected a total of 372 studies, of which five met inclusion criteria (two exploratory studies, two case reports, and one prospective study). These were included in the data evaluation. Effects of psychedelics on BDD and various ED symptoms were identified mostly through thematic analyses and self-reports.

conclusionsOur findings highlight that more research is needed to determine the safety and efficacy of psychedelics in BDD and EDs and we suggest avenues for future exploration.

Indexed as

Body Dysmorphic DisordersFeeding and Eating DisordersHallucinogensHumansProspective StudiesPsychotropic DrugsHallucinogensPsychotropic DrugsBody dysmorphic disordereating disorderhallucinogenspsychedelic-assisted psychotherapypsychedelics

Identifiers

PMID36515406
PMCPMC10197863
OpenAlexW4311498973

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.