Evidence map›Paper›PMID 36515333›Full record

Trial reportRevista do Colegio Brasileiro de Cirurgioes2022

Impact of Pectoralis Nerve Block (PECS) on postoperative pain in patients submitted to mastectomy with lymphadenectomy.

Amanda Lira Dos Santos Leite, Frederico Theobaldo Ramos Rocha, Michelle Jacintha C Oliveira, Aldo Vieira Barros, Silvio Marcos Lima Dos Santos, Alberson Maylson Ramos DA Silva, Diego Windson DE Araújo Silvestre, Elson A C Folha Filho, Caroline C Ferro, Taina Santos Bezerra and 4 more

Open access · goldAbstract readClinical Trial, Phase III
In one paragraph

Trial report in Revista do Colegio Brasileiro de Cirurgioes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Amanda Lira Dos Santos Leite- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0002-2429-7713
Frederico Theobaldo Ramos Rocha- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0001-5828-3312
Michelle Jacintha C Oliveira- Universidade Federal de Alagoas, Programa de Pós Graduação em Ciências Médicas, Faculdade de Medicina - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-4554-467X
Aldo Vieira Barros- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0002-5426-4904
Silvio Marcos Lima Dos Santos- Santa Casa de Misericórdia de Maceió, Department of Anesthesiology - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-1874-5652
Alberson Maylson Ramos DA Silva- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0001-9528-8286
Diego Windson DE Araújo Silvestre- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-2756-8547
Elson A C Folha Filho- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-1122-3528
Caroline C Ferro- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-4261-7167
Taina Santos Bezerra- Santa Casa de Misericórdia de Maceió, Department of Oncology Surgery - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-2949-510X
Laercio P Fachin- Centro Universitário Jayme de Altavila - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0002-4621-3031
Dalmir Cavalcanti Santos- Faculdade Pernambucana de Saúde, Department of Estatistics - Recife - PE - Brasil.ORCID http://orcid.org/0000-0003-2187-4746
Carlos Alberto DE Carvalho Fraga- Universidade Federal de Alagoas, Programa de Pós Graduação em Ciências Médicas, Faculdade de Medicina - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0002-9564-9595
Carolinne Sales-Marques- Universidade Federal de Alagoas, Programa de Pós Graduação em Ciências Médicas, Faculdade de Medicina - Maceió - AL - Brasil.ORCID http://orcid.org/0000-0003-2902-0657
Santa Casa de Misericórdia de Marília · BRUniversidade Federal de Alagoas · BRFaculdade Frassinetti do Recife · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBreast cancer is the most common malignant neoplasm in women worldwide. Surgery has been traditional treatment and, generally, it´s mastectomy with lymphadenectomy, that can causes postoperative pain. Therefore, we seek to study regional anesthesic techniques that can minimize this effect, such as the interpectoral block (PECS).

methodsrandomized controlled study with 82 patients with breast cancer who underwent mastectomy with lymphadenectomy from January 2020 to October 2021 in oncology hospital.

interventionstwo randomized groups (control - exclusive general anesthesia and PECS group - received PECS block with levobupivacaine/ropivacaine and general anesthesia). We applied a questionnaire with Numeric Rating Scale for pain 24h after surgery. We used Shapiro-Wilk, Mann-Whitney and Chi-square tests, and analyzed the data in R version 4.0.0 (ReBEC).

resultsin the PECS group, 50% were pain-free 24h after surgery and in the control group it was 42.86%. The majority who presented pain classified it as mild pain (VAS from 1 to 3) - (42.50%) PECS group and (40.48%) control group (p=0.28). Only 17.50% consumed opioids in the PECS group, similar to the control group with 21.43%. (p=0.65). There was a low rate of complications such as PONV in both groups. In the subgroup analysis, there was no statistical difference between the groups that used levobupivacaine or ropivacaine regarding postoperative pain and opioid consumption. DISCUSSION: the studied group had a low rate of pain in the postoperative period and it influenced the statistical analysis. There wasn´t difference in postoperative pain in groups.

conclusionwas not possible to demonstrate better results with the association of the PECS block with total intravenous analgesia. Need further studies to assess the efficacy of the nerve block.

Indexed as

Breast NeoplasmsNerve BlockThoracic NervesAnalgesics, OpioidFemaleHumansLevobupivacaineLymph Node ExcisionMastectomyPostoperative PainRopivacaineAnalgesics, OpioidLevobupivacaineRopivacaine

Identifiers

PMID36515333
PMCPMC10578795
OpenAlexW4311661962

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.