Evidence map›Paper›PMID 36515008›Full record

ArticleFEBS open bio2023

Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow.

Jiadi Chen, Jingru Liu, Huifang Huang

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Jiadi ChenClinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0003-2328-6665
Jingru LiuCentral Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0001-5626-1216
Huifang HuangCentral Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0002-8548-028X
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumor suppressor Lkb1 is known to regulate the expression of forkhead box P3 (Foxp3), thereby maintaining the levels of Foxp3

Indexed as

Bone MarrowHematopoietic Stem CellsT-Lymphocytes, RegulatoryAnimalsCell DifferentiationForkhead Transcription FactorsMiceProtein Serine-Threonine KinasesForkhead Transcription FactorsProtein Serine-Threonine Kinasesdifferentiationhematopoietic stem cellshomeostasisLkb1Treg

Identifiers

PMID36515008
PMCPMC9900093
OpenAlexW4311479272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.