Evidence map›Paper›PMID 36514782›Full record

ArticleIEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium2020

Three-dimensional super-resolution ultrasound imaging of chicken embryos - A validation framework for analysis of microvascular morphology.

Ipek Oezdemir, Shelby Mohr-Allen, Kara E Peak, Victor Varner, Kenneth Hoyt

Abstract read
In one paragraph

Article in IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Advancements in Three-Dimensional Super-Resolution Ultrasound Imaging: A Narrative Review.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
  4. Article
  5. Evaluation of Nonlinear Contrast Pulse Sequencing for Use in Super-Resolution Ultrasound Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ipek OezdemirDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, USA.
Shelby Mohr-AllenDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, USA.
Kara E PeakDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, USA.
Victor VarnerDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, USA.
Kenneth HoytDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, USA.

Funding

3D Super-Resolution Ultrasound Imaging for Cancer Detection and Treatment MonitoringR01EB025841 · NIBIB · UNIVERSITY OF TEXAS DALLAS · PI HOYT, KENNETH · 2019 to 2022
$1.3M
NIBIB NIH HHS R01 EB025841
6 · The paper itself

Abstract

The purpose of this present study was to improve the quantification of microvascular networks depicted in three-dimensional (3D) super-resolution ultrasound (SR-US) images and compare results with matched brightfield microscopy and B-mode ultrasound (US) images. Standard contrast-enhanced US (CEUS) images were collected using a high-frequency US scanner (Vevo 3100, FUJIFILM VisualSonics Inc) equipped with an MX250 linear array transducer. Using a developing chicken embryo as our model system, US imaging was performed after administration of a custom microbubble (MB) contrast agent. Guided by stereo microscopy, MBs were introduced into a perfused blood vessel by microinjection with a glass capillary needle. Volume data was collected by mechanically scanning the US transducer throughout a tissue volume-of-interest (VOI) in 90 μm step increments. CEUS images were collected at each increment and stored as in-phase/quadrature (IQ) data (

Indexed as

chicken embryomicrobubble contrast agentsmicrovascular morphologysuper-resolution ultrasound

Identifiers

PMID36514782
PMCPMC9744579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.