Evidence map›Paper›PMID 36514780›Full record

ReviewMedComm2022

Targeting inorganic nanoparticles to tumors using biological membrane-coated technology.

Yuanyuan Zhang, Qian Chen, Yefei Zhu, Manman Pei, Kairuo Wang, Xiao Qu, Yang Zhang, Jie Gao, Huanlong Qin

Abstract readReview
In one paragraph

Review in MedComm, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuanyuan ZhangNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Qian ChenNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Yefei ZhuNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Manman PeiNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Kairuo WangNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Xiao QuNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Yang ZhangNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.
Jie GaoChanghai Clinical Research Unit Shanghai Changhai Hospital Naval Medical University Shanghai China.
Huanlong QinNanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inorganic nanoparticles have extensively revolutionized the effectiveness of cancer therapeutics due to their distinct physicochemical properties. However, the therapeutic efficiency of inorganic nanoparticles is greatly hampered by the complex tumor microenvironment, patient heterogeneity, and systemic nonspecific toxicity. The biomimetic technology based on biological membranes (cell- or bacteria-derived membranes) is a promising strategy to confer unique characteristics to inorganic nanoparticles, such as superior biocompatibility, prolonged circulation time, immunogenicity, homologous tumor targeting, and flexible engineering approaches on the surface, resulting in the enhanced therapeutic efficacy of inorganic nanoparticles against cancer. Therefore, a greater push toward developing biomimetic-based nanotechnology could increase the specificity and potency of inorganic nanoparticles for effective cancer treatment. In this review, we summarize the recent advances in biological membrane-coated inorganic nanoparticles in cancer precise therapy and highlight the different types of engineered approaches, applications, mechanisms, and future perspectives. The surface engineering of biological membrane can greatly enhance their targeting, intelligence, and functionality, thereby realizing stronger tumor therapy effects. Further advances in materials science, biomedicine, and oncology can facilitate the clinical translation of biological membrane-coated inorganic nanoparticles.

Indexed as

biological membranecancer therapyimmunomodulationinorganic nanoparticlestargeted delivery

Identifiers

PMID36514780
PMCPMC9732394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.