Evidence map›Paper›PMID 36514756›Full record

ArticleFood science & nutrition2022

The effects of biogenic amines in Chinese Huangjiu on the behavior of mice and hangover headache-related indices.

Wenmei Zhao, Zukang Fu, Xin Wang, Qingzhong Mao, Chunguang Luan, Shanbin Chen, Fengjie Zhang, Jiajun Yu, Yiping Yao, Yishu Li and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Wenmei ZhaoCollege of Life Science and Technology Guangxi University Nanning China.ORCID https://orcid.org/0000-0001-8081-4917
Zukang FuKuaijishan Shaoxing Rice Wine Co. Ltd. Shaoxing China.
Xin WangSchool of Food Science and Engineering Beijing Technology and Business University Beijing China.
Qingzhong MaoKuaijishan Shaoxing Rice Wine Co. Ltd. Shaoxing China.
Chunguang LuanChina National Research Institute of Food and Fermentation Industries Beijing China.
Shanbin ChenChina National Research Institute of Food and Fermentation Industries Beijing China.
Fengjie ZhangChina National Research Institute of Food and Fermentation Industries Beijing China.
Jiajun YuChina National Research Institute of Food and Fermentation Industries Beijing China.
Yiping YaoChina National Research Institute of Food and Fermentation Industries Beijing China.
Yishu LiChina National Research Institute of Food and Fermentation Industries Beijing China.
Feike HaoChina National Research Institute of Food and Fermentation Industries Beijing China.
Deliang WangChina National Research Institute of Food and Fermentation Industries Beijing China.
Nan LiCollege of Life Science and Technology Guangxi University Nanning China.
Jie HuangfuChina National Research Institute of Food and Fermentation Industries Beijing China.ORCID https://orcid.org/0000-0001-6261-1577
Chengtao WangSchool of Food Science and Engineering Beijing Technology and Business University Beijing China.
China National Research Institute of Food and Fermentation · CNBeijing Technology and Business University · CNGuangxi University · CNShaoxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huangjiu (Chinese rice wine) is a popular and traditional alcoholic beverage in China; however, the consumption of Huangjiu readily results in hangover symptoms. The aim of this study was to identify the main components associated with behavioral inhibition, headache, and the relevant mechanisms by using a mice hangover model. The results of an open-field experiment revealed that the key biogenic amine associated with mice behavior was histamine, which inhibited the behavior activity of mice in a dose-dependent manner. Moreover, histamine treatment decreased the levels of serotonin (5-HT) and 5-hydroxyindole acetic acid. In addition, the levels of dopamine and nitric oxide, which are associated with migraine, increased in the brain tissue of mice. In addition, the expression of receptor genes of 5-HT, including

Indexed as

5‐HTbiogenic aminesheadachehistamineHuangjiu

Identifiers

PMID36514756
PMCPMC9731562
OpenAlexW4292117582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.