ArticleSynthetic and systems biotechnology2023
Engineering microbes to overproduce natural products as agrochemicals.
Article in Synthetic and systems biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Engineering Yarrowia Lipolytica for De Novo Biosynthesis of Abscisic Acid.Biotechnology journal · 2026Article
- Biosynthetic Mechanisms of Plant Chlorogenic Acid from a Microbiological Perspective.Microorganisms · 2025Review
- Endophytic and Rhizospheric Microorganisms: An Alternative for Sustainable, Organic, and Regenerative Bioinput Formulations for Modern Agriculture.Microorganisms · 2025Review
- Harnessing Bacteriophages for Sustainable Crop Protection in the Face of Climate Change.Microbial biotechnology · 2025Review
- Systematic metabolic engineering ofSynthetic and systems biotechnology · 2025Article
- Microbes Saving Lives and Reducing Suffering.Microbial biotechnology · 2025Article
- Overexpression of RuBisCO form I and II genes inApplied and environmental microbiology · 2024Article
- Actinomycetes are a natural resource for sustainable pest control and safeguarding agriculture.Archives of microbiology · 2024Review
- Plant metabolism and synthetic biology.Synthetic and systems biotechnology · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current agricultural practices heavily rely on the excessive application of synthetic pesticides and fertilizers to meet the food demands of the increasing global population. This practice has several drawbacks including its negative impact on the environment and human health. Recently, the use of natural products has gained interest as alternatives to these synthetic agrochemicals due to their selective working mechanisms and biodegradability. In order to efficiently produce these natural agrochemicals, engineering microorganisms is emerging as an increasingly viable approach, and it is anticipated that it will have a significant market share in the near future. This approach manipulates the metabolism of microbes to manufacture the desired natural compounds from low-cost starting materials. This review discusses recent examples of this approach. The produced natural products can serve as biopesticides or plant growth regulators for the sustainable improvement of plant growth and disease control. The challenges in further developing these strategies are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.