ArticleClinical ophthalmology (Auckland, N.Z.)2022
Orbital Complications of Acute Invasive Fungal Rhinosinusitis: A New Challenge in the COVID-19 Convalescent Patients.
Article in Clinical ophthalmology (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Chronic Invasive Fungal Rhinosinusitis Managed With Surgical Debridement and Topical Amphotericin B Without Systemic Antifungal Therapy: A Report of Two Cases.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026Article
- Ophthalmic Complications Following Sinus Lifting Surgery: Case Report and Review of Literature.Clinical case reports · 2025Article
- The Relevance and Potential Role of Orbital Fat in Inflammatory Orbital Diseases: Implications for Diagnosis and Treatment.Ophthalmology and therapy · 2025Review
- Orbital aspergillosis in an immunocompromised man with no history of trauma: a case report.The Journal of international medical research · 2024Article
- Is low dose of liposomal amphotericin B effective in management of acute invasive fungal rhinosinusitis? Our conclusions from Al-Mowassat University Hospital, Syria: a prospective observational study.BMC infectious diseases · 2023Observational
Corrections and comments
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Authors and funding
3 authors.
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Abstract
Purpose: Increased incidence of acute invasive fungal rhinosinusitis (AIFR) in the setting of COVID-19 is undeniable. This can be attributed to its effect on innate immunity and extensive use of corticosteroids. The goal of our study was to assess the orbital complications of AIFR and its management in the COVID-19 convalescent patients. Methods: Our longitudinal prospective study included 45 patients with orbital complications of AIFR in recently recovered COVID-19 patients. We performed otorhinolaryngological, ophthalmological, and neurological examinations to monitor the manifestations of the disease. Computed tomography and contrast enhanced magnetic resonance imaging were performed to detect the extent of infection. Antifungal medications, surgical intervention, and general condition management were all provided to all the patients. Results: We reported pre-septal cellulitis, orbital cellulitis, and orbital apex syndrome in 18, 13, and 10 patients, respectively. Four patients had cavernous sinus thrombosis. Conclusion: Early diagnosis and treatment of AIFR can decrease the morbidity and mortality rate of affected patients.
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