Evidence map›Paper›PMID 36514376›Full record

ArticleInternational journal of nanomedicine2022

Biosynthesis and Characterization of Gold and Copper Nanoparticles from

Sammar Fathy ELhabal, Hanan Mohamed Elwy, Soha Hassanin, Ahmed A El-Rashedy, Alaaeldin Ahmed Hamza, Mohammad Ahmad Khasawneh

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Food science & nutrition · 2026
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  9. Green Synthesis ofBiomolecules · 2024
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  13. Green Synthesis of Zinc Oxide Nanoparticles fromInternational journal of nanomedicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sammar Fathy ELhabalDepartment of Pharmaceutics and Industrial Pharmacy, Modern University for Technology and Information, Cairo, Egypt.ORCID 0000-0002-7970-2288
Hanan Mohamed ElwyPharmaceutical Chemistry Department, National Organization for Drug Control and Research, Cairo, Egypt.
Soha HassaninBiochemistry Department, Modern University for Technology and information, Cairo, Egypt.ORCID 0000-0001-8568-1033
Ahmed A El-RashedyChemistry of Natural and Microbial Products Department, National Research Center (NRC), Giza, Egypt.
Alaaeldin Ahmed HamzaBiology Department, National Organization for Drug Control and Research, Giza, Egypt.ORCID 0000-0001-5450-1116
Mohammad Ahmad KhasawnehDepartment of Chemistry, United Arab Emirates University, Al-Ain, United Arab Emirates.ORCID 0000-0001-5853-8311
Modern University for Information and Technology · EGNational Organization for Drug Control and Research · EGUnited Arab Emirates University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Metal nanoparticle synthesis using plant has emerged as an eco-friendly, clean, and viable strategy alternative to chemical and physical approaches. Methods: The fruit extract of Results: UV-Vis spectra of the AuNPs and CuNPs showed peaks at the wavelengths of 530 nm and 440 nm, respectively. Transmission electron microscopy showed that nanoparticles exhibited a mainly spherical form, with a distribution range of 100 to 113 nm in diameter for AuNPs and of 130 to 135 nm in diameter for CuNPs. While energy-dispersive X-ray spectroscopy was able to confirm the existence of AuNPs and CuNPs. The alcoholic extract of the fruit SP was analyzed by GC-MS in order to identify whether or not it contained any active phytochemicals. Fourier-transform infrared spectra confirmed the presence capping functional biomolecules of SP on the surface of nanoparticles that acts as stabilizers. Analysis of the zeta potential revealed that NPs with high degree of stability, as demonstrated by a strong negative potential value in the range of 25.2 to 28.7 mV. Results showed that both green AuNPs and CuNPs have potential antimicrobial activity against human pathogens such gram-negative bacteria and gram-positive bacteria, with CuNPs having antimicrobial activity higher than AuNPs. In addition, AuNPs and CuNPs have promising antioxidant and anticancer properties when applied to MCF-7 and MDA-MB-231 breast cancer cells. Studies of molecular docking of SP bioactive compounds were conducted against methenyl tetrahydrofolate synthetase. Among all of them, Beta - Sitosterol was the most prominent. Conclusion: These AuNPs and CuNPs are particularly appealing in a variety of applications in the pharmaceutical and medicinal industries due to their economical and environmentally friendly production.

Indexed as

Metal NanoparticlesSalvadoraceaeAnti-Bacterial AgentsCopperFruitGoldGreen Chemistry TechnologyHumansMicrobial Sensitivity TestsMolecular Docking SimulationPlant ExtractsSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsCopperGoldPlant Extractsantibacterialanticancerantioxidantgreen nanoparticlesSalvadora persica

Identifiers

PMID36514376
PMCPMC9741820
OpenAlexW4310869933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.