ArticleThe international journal of behavioral nutrition and physical activity2022
Associations of physical activity intensity with incident cardiovascular diseases and mortality among 366,566 UK adults.
Article in The international journal of behavioral nutrition and physical activity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Pooled it
- Associations of Combined Moderate and Vigorous Physical Activity With All-Cause, Cardiovascular, and Cancer Mortality: A Cohort Study of 586 936 US Adults.Journal of the American Heart Association · 2026Article
- Accelerometer-measured physical activity fragmentation and incident cardiovascular diseases: a prospective cohort study.Nutrition journal · 2026Article
- Assessing the causal impact of leisure-time physical activity and screen time on lifespan: a Mendelian randomization study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- Association of Accelerometer-Measured Light-Intensity Physical Activity with Cardiovascular Diseases: A Large Cohort Study.Health data science · 2026Article
- Dyadic associations of physical activity intensity with fertility-related quality of life in infertile couples: an APIM analysis.Frontiers in public health · 2026Article
- Sex differences in the association of physical activity patterns with all-cause and cardiovascular mortality: a prospective cohort study from NHANES 2007-2018.Scientific reports · 2025Article
- Physical activity, Vitamin D, and all-cause/cardiovascular mortality: a prospective study in older Chinese adults.BMC geriatrics · 2025Article
- Article
- Time Spent Jogging/Running and Biological Aging in 4458 U.S. Adults: An NHANES Investigation.International journal of environmental research and public health · 2023Article
- Associations of physical activity types and intensity with cardiovascular diseases by age and gender among 18,730 Chinese adults.Scientific reports · 2023Article
- Physical Activity Over the Lifecourse and Cardiovascular Disease.Circulation research · 2023Review
- A novel nomogram for predicting cardiometabolic diseases from modifiable risks in middle-aged adults-implication for health education.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe associations of the proportion of vigorous physical activity (VPA) to moderate to vigorous physical activity (MVPA) with incident cardiovascular disease (CVD) and all-cause mortality are unclear.
methodsThe present study included 366,566 participants (aged 40-69 years) without baseline CVD from the UK biobank during 2006 to 2010. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for risks of outcomes.
resultsDuring a median 11.8 years of follow-up, among 366,566 participants (mean age [SD]: 56.0 [8.1]), 31,894 incident CVD and 19,823 total deaths were documented. Compared with no VPA, 0%-30% of VPA to MVPA was associated with 12% and 19% lower risks of incident CVD (HR, 0.88 [95% CI, 0.86-0.91]) and all-cause mortality (HR, 0.81 [95% CI, 0.78-0.84]), respectively. Furthermore, we found that the maximum reduction of risks of incident CVD and all-cause mortality occurred at performing approximately 30% of VPA to MVPA (P < 0.001). Compared with participants reporting the lowest levels of MVPA (moderate physical activity [MPA], 0-150 min/week; VPA, 0-75 min/week), those performing 150-300 min/week of MPA and ≥ 150 min/week of VPA experienced the lowest risk of incident CVD (HR, 0.87 [95% CI, 0.79-0.95]) and all-cause mortality (HR, 0.71 [95% CI, 0.63-0.80]). Interestingly, we found that smokers yielded more cardiovascular benefits than non-smokers by performing a higher volume of VPA.
conclusionsComparing with UK adults reporting no VPA, engaging in 30% of VPA was associated with the lowest risk of incident CVD and all-cause mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.