Evidence map›Paper›PMID 36513966›Full record

ArticleBMC medical research methodology2022

Inferences for current chronic graft-versus-host-disease free and relapse free survival.

Xu Zhang, Scott R Solomon, Connie Sizemore

Abstract read
In one paragraph

Article in BMC medical research methodology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xu ZhangCenter for Clinical and Translational Sciences, The University of Texas Health Science Center at Houston, Houston, TX, US. Xu.Zhang@uth.tmc.edu.
Scott R SolomonThe Blood and Marrow Transplant Program at Northside Hospital, Atlanta, GA, US.
Connie SizemoreThe Blood and Marrow Transplant Program at Northside Hospital, Atlanta, GA, US.

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
Detection and evolution of diffusely abnormal white matter in multiple sclerosis: a deep learning approachR21NS118320 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HASAN, KHADER M · 2021 to 2022
$429k
NCATS NIH HHS UL1 TR003167NINDS NIH HHS R21 NS118320
6 · The paper itself

Abstract

This paper provides the methodologies of a new summary curve that measures the dynamic outcome following allogenic hematopoietic cell transplantation. This new summary curve computes the probabilities that a patient is alive in remission and free of severe-to-moderate chronic graft-versus-host disease (GVHD) over time. The probability is called Current chronic GVHD-free, Relapse-Free Survival (CGRFS). Based on a multistate model depicting the possible states that a patient may experience after transplant, CGRFS can be formulated as a linear combination of five survival functions. This method is known as the model-free approach. In this paper we provide the inferences of the model-free approach, including estimation of CGRFS, precision evaluation and comparison of CGRFS between two independent samples.

Indexed as

Bronchiolitis Obliterans SyndromeGraft vs Host DiseaseHematopoietic Stem Cell TransplantationChronic DiseaseDisease-Free SurvivalHumansRecurrenceGRFSKaplan-Meier estimatorMultistateProduct integral

Identifiers

PMID36513966
PMCPMC9746208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.