Evidence map›Paper›PMID 36513959›Full record

SynthesisCNS neuroscience & therapeutics2023

Aspiration versus stent retriever for posterior circulation stroke: A meta-analysis.

Xiumei Guo, Yu Xiong, Xinyue Huang, Zhigang Pan, Xiaodong Kang, Chunhui Chen, Jianfeng Zhou, Cui'e Wang, Shu Lin, Weipeng Hu and 2 more

Registry-linked trialAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in CNS neuroscience & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06733246 (Evaluation of the Safey & Performance of the Ceretrieve Device Designed for Thrombus Removal in Intracranial Arteries Using an Aspiration Technique in Patients Suffering an Acute Ischemic Stroke), which is not on this map. Cited by 7 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06733246 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of the Safey & Performance of the Ceretrieve Device Designed for Thrombus Removal in Intracranial Arteries Using an Aspiration Technique in Patients Suffering an Acute Ischemic Stroke (AIS)

TypeinterventionalSponsorCeretrieve Ltd.Ran2024 to 2027Enrolled132ConditionsAcute Ischemic StrokeArmsAspiration 0
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiumei GuoDepartment of Neurology, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Yu XiongDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Xinyue HuangDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Zhigang PanDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Xiaodong KangDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Chunhui ChenDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Jianfeng ZhouDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Cui'e WangDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Shu LinCentre of Neurological and Metabolic Research, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Weipeng HuDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Lingxing WangDepartment of Neurology, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
Feng ZhengDepartment of Neurosurgery, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.ORCID 0000-0002-4428-4450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsNew thrombectomy strategies have emerged recently. Differences between posterior circulation stroke management via aspiration and stent retriever remain to be evaluated. We compared the safety and efficacy of aspiration and stent retriever in treating posterior circulation stroke.

methodsThree databases (PubMed, Embase, and Cochrane Library) were systematically searched for studies comparing aspiration and stent retriever in patients with posterior circulation stroke. The modified Newcastle-Ottawa scale was used to assess the risk of bias. A random-effects model was used.

resultsFifteen cohort studies with 1451 patients were included. Pooled results showed a significant difference in total complication (odds ratio [OR] 0.48, 95% confidence interval [CI] [0.30, 0.76], p = 0.002). successful recanalization (1.85, [1.30, 2.64], p = 0.0006), favorable outcome (1.30, [1.02, 1.67], p = 0.04), procedure duration (-22.10, [-43.32, -0.88], p = 0.04), complete recanalization (4.96, [1.06, 23.16], p = 0.009), and first-pass effect (2.59, [1.55, 4.32], p = 0.0003) between the aspiration and stent retriever groups, and in favor of aspiration. There was no significant difference in the outcomes of rescue therapy (1.42, [0.66, 3.05], p = 0.37) between the two groups.

conclusionPatients with posterior circulation stroke receiving treatment with aspiration achieved better recanalization, first-pass effect, and shorter procedure time. Aspiration may be more secure than a stent retriever.

Indexed as

Brain IschemiaEndovascular ProceduresStrokeHumansRetrospective StudiesStentsThrombectomyTreatment Outcomeaspirationposterior circulation strokestent retrieverthrombectomy

Identifiers

PMID36513959
PMCPMC9873527

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.