ArticleJournal of child psychology and psychiatry, and allied disciplines2023
A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Environmental sensitivity and psychosocial characteristics in junior high school students with school refusal.Frontiers in psychiatry · 2026Article
- Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Common Genetic and Environmental Contributions to Anxiety Sensitivity, Anxiety, and Cognitive Symptoms of Eating Disorders in Adolescence.Research on child and adolescent psychopathology · 2025Article
- Genetics of environmental sensitivity and its association with variations in emotional problems, autistic traits, and wellbeing.Molecular psychiatry · 2024Article
- The interaction between polygenic risk and environmental influences: A direct test of the 3P model of insomnia in adolescents.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- 'Almost nothing is firmly established': A History of Heredity and Genetics in Mental Health Science.Wellcome open research · 2024Article
- Understanding and Managing Anxiety Sensitivity During Critical Illness and Long-Term Recovery.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDespite being considered a measure of environmental risk, reported life events are partly heritable. One mechanism that may contribute to this heritability is genetic influences on sensitivity, relating to how individuals process and interpret internal and external signals. The aim of this study was to explore the genetic and environmental overlap between self-reported life events and measures of sensitivity.
methodsAt age 17, 2,939 individuals from the Twins Early Development Study (TEDS) completed measures of anxiety sensitivity (Children's Anxiety Sensitivity Index), environmental sensitivity (Highly Sensitive Child Scale) and reported their experience of 20 recent life events. Using multivariate Cholesky decomposition models, we investigated the shared genetic and environmental influences on the associations between these measures of sensitivity and the number of reported life events, as well as both negative and positive ratings of life events.
resultsThe majority of the associations between anxiety sensitivity, environmental sensitivity and reported life events were explained by shared genetic influences (60%-75%), with the remainder explained by nonshared environmental influences (25%-40%). Environmental sensitivity showed comparable genetic correlations with both negative and positive ratings of life events (r
conclusionDifferences in how individuals process the contextual aspects of the environment or interpret their own physical and emotional response to environmental stimuli may be one mechanism through which genetic liability influences the subjective experience of life events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.