Evidence map›Paper›PMID 36513290›Full record

ArticleNeuroImage2023

BrainStat: A toolbox for brain-wide statistics and multimodal feature associations.

Sara Larivière, Şeyma Bayrak, Reinder Vos de Wael, Oualid Benkarim, Peer Herholz, Raul Rodriguez-Cruces, Casey Paquola, Seok-Jun Hong, Bratislav Misic, Alan C Evans and 2 more

Abstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Article
  3. Functional Brain Asymmetry Reveals Heterogeneous Subtypes in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2026
    Article
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  9. Review
  10. Macroscale Gradient-Informed Neural Oscillation Topography in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sara LarivièreMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Şeyma BayrakMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Reinder Vos de WaelMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Oualid BenkarimMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Peer HerholzMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Raul Rodriguez-CrucesMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Casey PaquolaInstitute of Neuroscience and Medicine (INM-1), Forschungszentrum Jülich, Germany.
Seok-Jun HongChild Mind Institute, New York, USA; Center for Neuroscience Imaging Research, Institute for Basic Science, and Department of Biomedical Engineering, Sungkyunkwan University, Suwon, South Korea.
Bratislav MisicMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Alan C EvansMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Sofie L ValkMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Institute of Neuroscience and Medicine (INM-1), Forschungszentrum Jülich, Germany. Electronic address: valk@cbs.mpg.de.
Boris C BernhardtMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada. Electronic address: boris.bernhardt@gmail.com.

Funding

Resource DiscoveryP41EB019936 · NIBIB · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI David Nelson Kennedy · 2016 to 2026
$15.2M
Large-scale meta-analysis of functional MRI dataR01MH096906 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI Alejandro De La Vega · 2012 to 2026
$7.9M
NIBIB NIH HHS P41 EB019936NIMH NIH HHS R01 MH096906
6 · The paper itself

Abstract

Analysis and interpretation of neuroimaging datasets has become a multidisciplinary endeavor, relying not only on statistical methods, but increasingly on associations with respect to other brain-derived features such as gene expression, histological data, and functional as well as cognitive architectures. Here, we introduce BrainStat - a toolbox for (i) univariate and multivariate linear models in volumetric and surface-based brain imaging datasets, and (ii) multidomain feature association of results with respect to spatial maps of post-mortem gene expression and histology, task-based fMRI meta-analysis, as well as resting-state fMRI motifs across several common surface templates. The combination of statistics and feature associations into a turnkey toolbox streamlines analytical processes and accelerates cross-modal research. The toolbox is implemented in both Python and MATLAB, two widely used programming languages in the neuroimaging and neuroinformatics communities. BrainStat is openly available and complemented by an expandable documentation.

Indexed as

BrainSoftwareData Interpretation, StatisticalDatasets as TopicHumansLinear ModelsMagnetic Resonance ImagingMeta-Analysis as TopicNeuroimagingMultivariate analysisNeuroimagingUnivariate analysis

Identifiers

PMID36513290
PMCPMC10715099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.