Evidence map›Paper›PMID 36512600›Full record

ArticlePloS one2022

Accuracy of the electronic health record's problem list in describing multimorbidity in patients with heart failure in the emergency department.

Brandon L King, Michelle L Meyer, Srihari V Chari, Karen Hurka-Richardson, Thomas Bohrmann, Patricia P Chang, Jo Ellen Rodgers, Jan Busby-Whitehead, Martin F Casey

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Attitudes Toward Deprescribing Among Older Adults Seeking Care in the Emergency Department.Journal of the American College of Emergency Physicians open · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Prevalence of fall risk-increasing drugs in older adults presenting with falls to the emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brandon L KingDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Michelle L MeyerDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Srihari V ChariDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.ORCID 0000-0003-2920-7104
Karen Hurka-RichardsonDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Thomas BohrmannAnalytical Partners Consulting LLC, Raleigh, North Carolina, United States of America.
Patricia P ChangDivision of Cardiology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Jo Ellen RodgersDivision of Pharmacotherapy and Experimental Therapeutics, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America.
Jan Busby-WhiteheadDivision of Geriatric Medicine and Center of Aging and Health, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Martin F CaseyDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-5049-012X

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
UNC-CH ISTEM ProgramT35HL134624 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Jane Brice, Michelle Meyer · 2017 to 2026
$347k
NCATS NIH HHS UL1 TR002489NHLBI NIH HHS T35 HL134624
6 · The paper itself

Abstract

Patients with heart failure (HF) often suffer from multimorbidity. Rapid assessment of multimorbidity is important for minimizing the risk of harmful drug-disease and drug-drug interactions. We assessed the accuracy of using the electronic health record (EHR) problem list to identify comorbid conditions among patients with chronic HF in the emergency department (ED). A retrospective chart review study was performed on a random sample of 200 patients age ≥65 years with a diagnosis of HF presenting to an academic ED in 2019. We assessed participant chronic conditions using: (1) structured chart review (gold standard) and (2) an EHR-based algorithm using the problem list. Chronic conditions were classified into 37 disease domains using the Agency for Healthcare Research Quality's Elixhauser Comorbidity Software. For each disease domain, we report the sensitivity, specificity, positive predictive value, and negative predictive of using an EHR-based algorithm. We calculated the intra-class correlation coefficient (ICC) to assess overall agreement on Elixhauser domain count between chart review and problem list. Patients with HF had a mean of 5.4 chronic conditions (SD 2.1) in the chart review and a mean of 4.1 chronic conditions (SD 2.1) in the EHR-based problem list. The five most prevalent domains were uncomplicated hypertension (90%), obesity (42%), chronic pulmonary disease (38%), deficiency anemias (33%), and diabetes with chronic complications (30.5%). The positive predictive value and negative predictive value of using the EHR-based problem list was greater than 90% for 24/37 and 32/37 disease domains, respectively. The EHR-based problem list correctly identified 3.7 domains per patient and misclassified 2.0 domains per patient. Overall, the ICC in comparing Elixhauser domain count was 0.77 (95% CI: 0.71-0.82). The EHR-based problem list captures multimorbidity with moderate-to-good accuracy in patient with HF in the ED.

Indexed as

Heart FailureMultimorbidityAgedChronic DiseaseElectronic Health RecordsEmergency Service, HospitalHumansRetrospective Studies

Identifiers

PMID36512600
PMCPMC9747000

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.