Evidence map›Paper›PMID 36512582›Full record

ArticlePloS one2022

Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view.

Alice R Motschi, Florian Schwarzhans, Sylvia Desissaire, Stefan Steiner, Hrvoje Bogunović, Philipp K Roberts, Clemens Vass, Christoph K Hitzenberger, Michael Pircher

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alice R MotschiCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-0804-2304
Florian SchwarzhansCenter for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Sylvia DesissaireCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Stefan SteinerDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Hrvoje BogunovićChristian Doppler Laboratory for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria.
Philipp K RobertsDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Clemens VassDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-4756-9088
Christoph K HitzenbergerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Michael PircherCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

Funding

Austrian Science Fund FWF KLI 749Austrian Science Fund FWF P 30378
6 · The paper itself

Abstract

We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.

Indexed as

GlaucomaRetinal Pigment EpitheliumFluorescein AngiographyHealth StatusHumansRefraction, OcularTomography, Optical Coherence

Identifiers

PMID36512582
PMCPMC9746957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.