Evidence map›Paper›PMID 36512503›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

A smartphone intervention that enhances real-world memory and promotes differentiation of hippocampal activity in older adults.

Chris B Martin, Bryan Hong, Rachel N Newsome, Katarina Savel, Melissa E Meade, Andrew Xia, Christopher J Honey, Morgan D Barense

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Technology that CARES: Enhancing dementia care through everyday technologies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  8. Article
  9. Article
  10. Memory selectivity in older age.Current opinion in psychology · 2024
    Review
  11. A smartphone intervention that enhances real-world memory and promotes differentiation of hippocampal activity in older adults.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chris B MartinDepartment of Psychology, Florida State University, Tallahassee, FL, 32306.ORCID 0000-0002-7014-4371
Bryan HongDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.ORCID 0000-0001-8432-8182
Rachel N NewsomeDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.
Katarina SavelDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.ORCID 0000-0003-2292-9892
Melissa E MeadeDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.
Andrew XiaDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.
Christopher J HoneyDepartment of Psychological & Brain Sciences, Johns Hopkins University, Baltimore, MD, 21218.ORCID 0000-0002-0745-5089
Morgan D BarenseDepartment of Psychology, University of Toronto, Toronto, ON, M5S 3G3 Canada.

Funding

CIHR PJT-126003CIHR PJT-173336
6 · The paper itself

Abstract

The act of remembering an everyday experience influences how we interpret the world, how we think about the future, and how we perceive ourselves. It also enhances long-term retention of the recalled content, increasing the likelihood that it will be recalled again. Unfortunately, the ability to recollect event-specific details and reexperience the past tends to decline with age. This decline in recollection may reflect a corresponding decrease in the distinctiveness of hippocampal memory representations. Despite these well-established changes, there are few effective cognitive behavioral interventions that target real-world episodic memory. We addressed this gap by developing a smartphone-based application called HippoCamera that allows participants to record labeled videos of everyday events and subsequently replay, high-fidelity autobiographical memory cues. In two experiments, we found that older adults were able to easily integrate this noninvasive intervention into their daily lives. Using HippoCamera to repeatedly reactivate memories for real-world events improved episodic recollection and it evoked more positive autobiographical sentiment at the time of retrieval. In both experiments, these benefits were observed shortly after the intervention and again after a 3-mo delay. Moreover, more detailed recollection was associated with more differentiated memory signals in the hippocampus. Thus, using this smartphone application to systematically reactivate memories for recent real-world experiences can help to maintain a bridge between the present and past in older adults.

Indexed as

Memory, EpisodicSmartphoneAgedCuesHippocampusHumansMental Recallagingautobiographical memoryepisodic memoryfMRIhippocampus

Identifiers

PMID36512503
PMCPMC9907156

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.