Evidence map›Paper›PMID 36512353›Full record

ArticleJAMA network open2022

Hospitalizations Associated With Mental Health Conditions Among Adolescents in the US and France During the COVID-19 Pandemic.

Alba Gutiérrez-Sacristán, Arnaud Serret-Larmande, Meghan R Hutch, Carlos Sáez, Bruce J Aronow, Surbhi Bhatnagar, Clara-Lea Bonzel, Tianxi Cai, Batsal Devkota, David A Hanauer and 18 more

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Predicting Psychiatric Readmission of Children and Adolescents Using Machine Learning.Journal of child and adolescent psychopharmacology · 2026
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  16. The impact of COVID-19 on psychiatric clinical encounters among low-income racially-diverse children.Journal of child psychology and psychiatry, and allied disciplines · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 11 institutions in 4 countries.

Alba Gutiérrez-SacristánDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Arnaud Serret-LarmandeDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Meghan R HutchDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Carlos SáezBiomedical Data Science Lab, Instituto Universitario de Tecnologías de la Información y Comunicaciones, Universitat Politècnica de València, València, Spain.
Bruce J AronowDepartment of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Surbhi BhatnagarDepartment of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Clara-Lea BonzelDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Tianxi CaiDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Batsal DevkotaDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
David A HanauerDepartment of Learning Health Sciences, University of Michigan Medical School, Ann Arbor.
Ne Hooi Will LohDepartment of Anaesthesia, National University Health System, Singapore.
Yuan LuoDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Bertrand MoalUnité Informatique et Archivistique Médicale, Bordeaux University Hospital, Bordeaux, France.
Taha Mohseni AhooyiDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Wanjiku F M NjorogeDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia.
Gilbert S OmennDepartment of Learning Health Sciences, University of Michigan Medical School, Ann Arbor.
L Nelson Sanchez-PintoDepartment of Pediatrics (Critical Care), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Andrew M SouthDepartment of Pediatrics-Section of Nephrology, Brenner Children's, Wake Forest University School of Medicine, Winston Salem, North Carolina.
Francesca SperottoDepartment of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Amelia L M TanDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Deanne M TaylorDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Guillaume VerdyUnité Informatique et Archivistique Médicale, Bordeaux University Hospital, Bordeaux, France.
Shyam VisweswaranDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Zongqi XiaDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Janet ZahnerDepartment of Information Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Paul AvillachDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.
Florence T BourgeoisComputational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts.
Consortium for Clinical Characterization of COVID-19 by EHR (4CE)
Harvard University · USBoston Children's Hospital · USChildren's Hospital of Philadelphia · USCincinnati Children's Hospital Medical Center · USNorthwestern University · USUniversity of Michigan–Ann Arbor · USUniversity of Pittsburgh · USNational University Health System · SGUniversitat Politècnica de València · ESUniversity of Pennsylvania · USWake Forest University · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STUART A BATTERMAN · 2011 to 2026
$21.3M
The LungMAP Data Coordination Center for Next Gen Systems Biology of RespirationU24HL148865 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Bruce J Aronow, Nathan G. Salomonis · 2019 to 2026
$12.4M
CRITICAL: Collaborative Resource for Intensive care Translational science, Informatics, Comprehensive Analytics, and LearningU01TR003528 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIMINO, JAMES J, LUO, YUAN · 2021 to 2024
$4.9M
Statistical Methods for Optimizing Personalized Treatment SelectionR01HL089778 · NHLBI · STANFORD UNIVERSITY · PI LU TIAN · 2008 to 2026
$4.8M
Pediatric COVID-19 Severity Dashboard During Delta Variant CirculationR01HD105939 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Tellen Bennett, Lazaro Nelson Sanchez-Pinto · 2021 to 2026
$4.6M
Leveraging electronic health records to optimize treatment selection and response in multiple sclerosisR01NS098023 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Zongqi Xia · 2016 to 2026
$4.6M
Modeling the Incompleteness and Biases of Health DataR01LM013337 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2020 to 2023
$1.3M
Real-world impact of the COVID-19 pandemic in people with multiple sclerosisR01NS124882 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI XIA, ZONGQI · 2022 to 2024
$1.2M
Predoctoral Training Program in Biomedical Data Driven Discovery (BD3)T32LM012203 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KLABJAN, DIEGO, STARREN, JUSTIN B. · 2015 to 2019
$1.1M
British Heart Foundation FS/19/52/34563NCATS NIH HHS U01 TR003528NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001857NCATS NIH HHS UL1 TR002240NHLBI NIH HHS K23 HL148394NHLBI NIH HHS L40 HL148910NHLBI NIH HHS R01 HL089778NHLBI NIH HHS U24 HL148865NICHD NIH HHS R01 HD105939NIEHS NIH HHS P30 ES017885NINDS NIH HHS R01 NS098023NINDS NIH HHS R01 NS124882NLM NIH HHS R01 LM013337NLM NIH HHS T32 LM012203
6 · The paper itself

Abstract

Importance: The COVID-19 pandemic has been associated with an increase in mental health diagnoses among adolescents, though the extent of the increase, particularly for severe cases requiring hospitalization, has not been well characterized. Large-scale federated informatics approaches provide the ability to efficiently and securely query health care data sets to assess and monitor hospitalization patterns for mental health conditions among adolescents. Objective: To estimate changes in the proportion of hospitalizations associated with mental health conditions among adolescents following onset of the COVID-19 pandemic. Design, Setting, and Participants: This retrospective, multisite cohort study of adolescents 11 to 17 years of age who were hospitalized with at least 1 mental health condition diagnosis between February 1, 2019, and April 30, 2021, used patient-level data from electronic health records of 8 children's hospitals in the US and France. Main Outcomes and Measures: Change in the monthly proportion of mental health condition-associated hospitalizations between the prepandemic (February 1, 2019, to March 31, 2020) and pandemic (April 1, 2020, to April 30, 2021) periods using interrupted time series analysis. Results: There were 9696 adolescents hospitalized with a mental health condition during the prepandemic period (5966 [61.5%] female) and 11 101 during the pandemic period (7603 [68.5%] female). The mean (SD) age in the prepandemic cohort was 14.6 (1.9) years and in the pandemic cohort, 14.7 (1.8) years. The most prevalent diagnoses during the pandemic were anxiety (6066 [57.4%]), depression (5065 [48.0%]), and suicidality or self-injury (4673 [44.2%]). There was an increase in the proportions of monthly hospitalizations during the pandemic for anxiety (0.55%; 95% CI, 0.26%-0.84%), depression (0.50%; 95% CI, 0.19%-0.79%), and suicidality or self-injury (0.38%; 95% CI, 0.08%-0.68%). There was an estimated 0.60% increase (95% CI, 0.31%-0.89%) overall in the monthly proportion of mental health-associated hospitalizations following onset of the pandemic compared with the prepandemic period. Conclusions and Relevance: In this cohort study, onset of the COVID-19 pandemic was associated with increased hospitalizations with mental health diagnoses among adolescents. These findings support the need for greater resources within children's hospitals to care for adolescents with mental health conditions during the pandemic and beyond.

Indexed as

COVID-19PandemicsAdolescentChildCohort StudiesFemaleHospitalizationHumansMaleMental HealthRetrospective StudiesSARS-CoV-2

Identifiers

PMID36512353
PMCPMC9856226
OpenAlexW4311249176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.