Evidence map›Paper›PMID 36512203›Full record

ArticleProbiotics and antimicrobial proteins2024

Feeding Broiler Chicks with Bacillus subtilis, Clostridium butyricum, and Enterococcus faecalis Mixture Improves Growth Performance and Regulates Cecal Microbiota.

De Xin Dang, Qiangqiang Zou, Yunhe Xu, Yan Cui, Xu Li, Yingying Xiao, Tieliang Wang, Desheng Li

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microorganisms · 2025
    Article
  5. Article
  6. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  7. Article
  8. Frontiers in veterinary science · 2025
    Review
  9. Heat-killedFrontiers in microbiology · 2025
    Article
  10. Postbiotic derived fromFrontiers in veterinary science · 2024
    Article
  11. Frontiers in veterinary science · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

De Xin Dang *College of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China.
Qiangqiang Zou *College of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China.
Yunhe XuCollege of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China.
Yan CuiCollege of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China.
Xu LiLiaoning Kaiwei Biotechnology Co., Ltd., Jinzhou, 121000, China.
Yingying XiaoLiaoning Kaiwei Biotechnology Co., Ltd., Jinzhou, 121000, China.
Tieliang WangCollege of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China.
Desheng LiCollege of Animal Science and Veterinary Medicine, Jinzhou Medical University, Jinzhou, 121001, China. lidesheng0726521@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 300 day-old Arbor Acres Plus broiler chicks (mixed sex) was used to evaluate the effects of dietary supplementation of Bacillus subtilis, Clostridium butyricum, and Enterococcus faecalis mixture (PB) on growth performance, ileal morphology, and cecal microbiota. All birds were randomly assigned into 3 groups based on the initial body weight. There were 5 replicate cages per group and 20 birds per cage. The experimental period was 42 days. Dietary treatments were based on a basal diet and supplemented with 0, 0.05, or 0.10% PB. The results indicated that broiler chicks fed with the diet supplemented with graded levels of PB have quadratically improved their body weight gain and feed intake; the highest value was presented in 0.05% PB-containing group. In addition, villus to crypt ratio linearly increased with the concentration of PB increased in the diet. The alpha diversity linearly increased by PB supplementation, and the highest value was presented in 0.10% PB-containing group. In terms of growth performance, the suitable dose of PB used in the diet was 0.05%. However, ternary plot showed that the harmful bacteria, Escherichia-Shigella, was enriched in 0.05% PB-containing group. In brief, we considered that dietary supplementation of graded levels of PB improved growth performance and regulated cecal microbiota in broiler chicks.

Indexed as

Clostridium butyricumMicrobiotaProbioticsAnimal FeedAnimalsBacillus subtilisBody WeightChickensDietDietary SupplementsEnterococcus faecalis16S rRNABroiler chicksCecal microbiotaGrowth performanceIntestinal morphologyProbiotic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.