Evidence map›Paper›PMID 36512102›Full record

SynthesisNeurosurgical review2022

Genetic association between the lncRNA ANRIL rs10757272 polymorphism and intracranial aneurysm susceptibility in Asians.

Wei Zhao, Aijie He, Peng Zou

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wei ZhaoDepartment of Neurosurgery, Yuhuangding Hospital of Yantai, Peng Zou, No. 20, Yuhuangding East Road, Zhifu District, Yantai, 264000, Shandong, China.
Aijie HeDepartment of Neurosurgery, Yuhuangding Hospital of Yantai, Peng Zou, No. 20, Yuhuangding East Road, Zhifu District, Yantai, 264000, Shandong, China.
Peng ZouDepartment of Neurosurgery, Yuhuangding Hospital of Yantai, Peng Zou, No. 20, Yuhuangding East Road, Zhifu District, Yantai, 264000, Shandong, China. ytyhdns@126.com.ORCID http://orcid.org/0000-0002-7401-2149
Yuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current epidemiological studies reporting the role of lncRNA ANRIL rs10757272 polymorphism and intracranial aneurysm risk remain controversial. In the present study, we conducted a meta-analysis to resolve this inconsistency. PubMed and EMBASE databases were retrieved to collect the publications evaluating the association with a time limit of August 20, 2021. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the strength of the association. Subgroup analysis, heterogeneity analyses, and publication bias were assessed in the meta-analysis. Finally, 2853 cases and 13,426 controls were enrolled in this meta-analysis based on inclusion criteria. The pooled results indicated that the rs10757272 polymorphism is significantly associated with the risk of intracranial aneurysms in all genetic models (homozygous model, odds ratio (OR) = 1.48, 95% confidence interval (CI) = 1.28-1.71, P

Indexed as

Intracranial AneurysmRNA, Long NoncodingAsianGenetic Predisposition to DiseaseHumansOdds RatioPolymorphism, Single NucleotideRisk FactorsCDKN2B antisense RNA, humanRNA, Long NoncodingANRILIntracranial aneurysmsMeta-analysisPolymorphism

Identifiers

PMID36512102
OpenAlexW4311387398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.