ArticleEuropean radiology2023
Capability of arterial spin labeling and intravoxel incoherent motion diffusion-weighted imaging to detect early kidney injury in chronic kidney disease.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- The value of functional magnetic resonance imaging in the evaluation of diabetic kidney disease: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Capability of arterial spin labeling combined with morphological characteristics to distinguish early- and mid-stage chronic kidney disease: a prospective study on 5 T MRI.Quantitative imaging in medicine and surgery · 2026Article
- Virtual MR elastography with diffusion-weighted imaging to evaluate chronic kidney disease fibrosis and dysfunction.Radiology advances · 2026Article
- Multiparametric MRI for Early Chronic Kidney Disease Detection: Insights Into Renal Microcirculation.NMR in biomedicine · 2026Article
- Integrating kidney imaging for risk prediction, therapeutic monitoring, and prognostication across the kidney disease spectrum: a review of emerging evidence.Clinical kidney journal · 2026Review
- Value of multiparametric MRI as a potential marker to differentiate membranous nephropathy from IgA nephropathy.BMC medical imaging · 2026Article
- Machine Learning with Multiparametric MRI and Clinical Biomarkers for Noninvasive Renal Interstitial Fibrosis Staging.Bioengineering (Basel, Switzerland) · 2026Article
- Automated Coregistered Segmentation for Volumetric Analysis of Multiparametric Renal MRI.Magnetic resonance in medicine · 2026Article
- Assessment of renal interstitial fibrosis in glomerulonephritis using compartmental and non-compartmental diffusion magnetic resonance imaging.La Radiologia medica · 2026Article
- Multiparametric functional MRI for early detection of renal impairment: clinical applications and future directions.Abdominal radiology (New York) · 2026Review
- Contrast-free functional MRI for assessing renal involvement in patients with ANCA-associated vasculitis.BMC nephrology · 2026Article
- Insight into Kidney Function and Microstructure Through Renal MRI-Review of the Literature.Bioengineering (Basel, Switzerland) · 2026Review
- Nomograms with arterial spin labeling for diagnosing early-stage chronic kidney disease.International urology and nephrology · 2026Article
- In vivo study of intravoxel incoherent motion imaging in assessing obesity-related kidney injury.BMC medical imaging · 2026Article
- Dual-center validation of a multi-sequence MRI radiomics nomogram for noninvasive assessment of renal fibrosis in chronic kidney disease.BMC medical imaging · 2026Article
- Article
- Quantitative assessment of renal function and perfusion changes in membranous nephropathy using multiparametric magnetic resonance imaging.Insights into imaging · 2026Article
- Early diagnosis of radiation-induced renal injury: from lagging indicators to multimodal, pre-fibrotic detection.Frontiers in cell and developmental biology · 2026Review
- Quantitative Parameters Derived Using the Biexponential and Stretched Exponential Models for the Detection of Early Renal Impairment in Chronic Kidney Disease.Current medical imaging · 2025Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesTo prospectively investigate the capability of arterial spin labeling (ASL) and intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) for the identification of early kidney injury in chronic kidney disease (CKD) patients with normal estimated glomerular filtration rate (eGFR).
methodsFifty-four CKD patients confirmed by renal biopsy (normal eGFR group [eGFR ≥ 90 mL/min/1.73 m
resultsThe renal cortical D, D*, f, and RBF values showed statistically significant differences among the three groups. eGFR was positively correlated with MRI parameters (D: r = 0.299, D*: r = 0.569, f: r = 0.733, RBF: r = 0.586). The areas under the curve (AUCs) for discriminating CKD patients from HV were 0.725, 0.752, 0.947, and 0.884 by D, D*, f, and RBF, respectively. D, D*, f, RBF, and eGFR identified CKD patients with normal eGFR with AUCs of 0.735, 0.612, 0.917, 0.827, and 0.733, respectively, and AUC of f value was significantly larger than that of eGFR.
conclusionIVIM-DWI and ASL were useful for detecting underlying pathologic injury in early CKD patients with normal eGFR. KEY POINTS: • The renal cortical f and RBF values in the control group were significantly higher than those in the normal eGFR group. • A negative correlation was observed between the renal cortical D, D*, f, and RBF values and SCr and 24 h-UPRO, while eGFR was significantly positively correlated with renal cortical D, D*, f, and RBF values. • The AUC of renal cortical f values was statistically larger than that of eGFR for the discrimination between the CKD with normal eGFR group and the control group.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.