Evidence map›Paper›PMID 36511780›Full record

ArticleeLife2022

Monoallelic

Ethiraj Ravindran, Nobuto Arashiki, Lena-Luise Becker, Kohtaro Takizawa, Jonathan Lévy, Thomas Rambaud, Konstantin L Makridis, Yoshio Goshima, Na Li, Maaike Vreeburg and 6 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  10. Case report: AFrontiers in neuroscience · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 5 countries.

Ethiraj Ravindran *Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-0095-116X
Nobuto Arashiki *Department of Biochemistry, Tokyo Women's Medical University, Tokyo, Japan.
Lena-Luise Becker *Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Kohtaro Takizawa *Department of Biochemistry, Tokyo Women's Medical University, Tokyo, Japan.
Jonathan LévyDepartment of Genetics, Robert Debré University Hospital, Paris, France.
Thomas RambaudLaboratoire de biologie médicale multisites Seqoia, Paris, France.
Konstantin L MakridisDepartment of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-2609-4557
Yoshio GoshimaDepartment of Molecular Pharmacology and Neurobiology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Na LiLaboratory of Medical Systems Biology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Maaike VreeburgClinical Genetics, Maastricht University Medical Centre, Maastricht, Netherlands.
Bénédicte DemeerCenter for Human Genetics, CLAD Nord de France, CHU Amiens-Picardie, Amiens, France.
Achim DickmannsDepartment of Molecular Structural Biology, Institute for Microbiology and Genetics, Georg-August-University Göttingen, Göttingen, Germany.
Alexander P A StegmannClinical Genetics, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID https://orcid.org/0000-0002-9736-7137
Hao HuLaboratory of Medical Systems Biology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-3567-609X
Fumio NakamuraDepartment of Biochemistry, Tokyo Women's Medical University, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2029-6083
Angela M KaindlDepartment of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-9454-206X
Charité - Universitätsmedizin Berlin · DETokyo Women's Medical University · JPGuangzhou Medical University · CNMaastricht University Medical Centre · NLCentre Hospitalier Universitaire Amiens-Picardie · FRHôpital Robert-Debré · FRUniversity of Göttingen · DEYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collapsin response mediator proteins (CRMPs) are key for brain development and function. Here, we link CRMP1 to a neurodevelopmental disorder. We report heterozygous de novo variants in the

Indexed as

Autism Spectrum DisorderIntellectual DisabilityNeurodevelopmental DisordersAnimalsCollapsin Response Mediator Protein 1HumansMiceMuscle HypotoniaNeuronal OutgrowthNeuronsCollapsin Response Mediator Protein 1CRMP1 protein, humanautism spectrum disorderCRMP1geneticsgenomicshumanintellectual disabilityneurodevelopmental disorderneuroscience

Identifiers

PMID36511780
PMCPMC9803352
OpenAlexW4311292193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.