Evidence map›Paper›PMID 36511691›Full record

ArticleMicrobiology spectrum2023

Predicting Antigenic Distance from Genetic Data for PRRSV-Type 1: Applications of Machine Learning.

Dennis N Makau, Cinta Prieto, Francisco J Martínez-Lobo, I A D Paploski, Kimberly VanderWaal

Abstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dennis N MakauDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, USA.ORCID 0000-0002-1802-2545
Cinta PrietoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain.
Francisco J Martínez-LoboDepartament de Ciència Animal, ETSEA-Universitat de Lleida, Lleida, Spain.
I A D PaploskiDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, USA.
Kimberly VanderWaalDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, USA.

Funding

Biotechnology and Biological Sciences Research Council BB/T004401/1
6 · The paper itself

Abstract

The control of porcine reproductive and respiratory syndrome (PRRS) remains a significant challenge due to the genetic and antigenic variability of the causative virus (PRRSV). Predominantly, PRRSV management includes using vaccines and live virus inoculations to confer immunity against PRRSV on farms. While understanding cross-protection among strains is crucial for the continued success of these interventions, understanding how genetic diversity translates to antigenic diversity remains elusive. We developed machine learning algorithms to estimate antigenic distance

Indexed as

Machine LearningPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusAnimalsAntigenic VariationCross ProtectionCross ReactionsGenetic VariationPhylogenySwinebioinformaticscross-protectionimmune responseimmunodominant sitesimmunogenicitymachine learningseroneutralization

Identifiers

PMID36511691
PMCPMC9927307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.