Evidence map›Paper›PMID 36511586›Full record

ArticleBioinformatics (Oxford, England)2023

Codetta: predicting the genetic code from nucleotide sequence.

Yekaterina Shulgina, Sean R Eddy

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  9. The cell biology and genome ofMolecular biology of the cell · 2025
    Article
  10. Mycology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yekaterina ShulginaDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-7658-9294
Sean R EddyDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-6676-4706

Funding

HMMER and Infernal: Finding distant homologs of sequences and RNA structuresR01HG009116 · NHGRI · HARVARD UNIVERSITY · PI EDDY, SEAN R · 2016 to 2025
$4.3M
Identifying genetic code reassignments in nucleotide sequence databasesF31HG010984 · NHGRI · HARVARD UNIVERSITY · PI SHULGINA, YEKATERINA · 2020 to 2021
$65k
Howard Hughes Medical InstituteNHGRI NIH HHS F31 HG010984NHGRI NIH HHS R01 HG009116
6 · The paper itself

Abstract

summaryCodetta is a Python program for predicting the genetic code table of an organism from nucleotide sequences. Codetta can analyze an arbitrary nucleotide sequence and needs no sequence annotation or taxonomic placement. The most likely amino acid decoding for each of the 64 codons is inferred from alignments of profile hidden Markov models of conserved proteins to the input sequence. AVAILABILITY AND IMPLEMENTATION: Codetta 2.0 is implemented as a Python 3 program for MacOS and Linux and is available from http://eddylab.org/software/codetta/codetta2.tar.gz and at http://github.com/kshulgina/codetta. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Genetic CodeSoftwareBase Sequence

Identifiers

PMID36511586
PMCPMC9825746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.