Evidence map›Paper›PMID 36511113›Full record

ArticleThe British journal of psychiatry : the journal of mental science2023

Modelling mood updating: a proof of principle study.

James E Clark, Stuart Watson

Abstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

James E ClarkTranslational and Clinical Research Institute, Newcastle University, UK.ORCID 0000-0001-5763-6200
Stuart WatsonTranslational and Clinical Research Institute, Newcastle University, UK; and Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, UK.ORCID 0000-0002-2558-3367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent developments in computational psychiatry have led to the hypothesis that mood represents an expectation (prior belief) on the likely interoceptive consequences of action (i.e. emotion). This stems from ideas about how the brain navigates its external world by minimising an upper bound on surprisal (free energy) of sensory information and echoes developments in other perceptual domains.

aimsIn this paper we aim to present a simple partial observable Markov decision process that models mood updating in response to stressful or non-stressful environmental fluctuations while seeking to minimise surprisal in relation to prior beliefs about the likely interoceptive signals experienced with specific actions (attenuating or amplifying stress and pleasure signals).

methodWe examine how, by altering these prior beliefs we can model mood updating in depression, mania and anxiety.

resultsWe discuss how these models provide a computational account of mood and its related psychopathology and relate it to previous research in reward processing.

conclusionsModels such as this can provide hypotheses for experimental work and also open up the potential modelling of predicted disease trajectories in individual patients.

Indexed as

BrainEmotionsAffectAnxiety DisordersHumansaetiologyanxiety disordersBipolar affective disorderscognitive neurosciencedepressive disorders

Identifiers

PMID36511113
PMCPMC9929713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.