Evidence map›Paper›PMID 36510703›Full record

ArticleGenes, brain, and behavior2023

Genome-wide assessment reveals a significant association between ACSS3 and physical activity.

Jinyeon Jo, Youngkyu Song, Dankyu Yoon, Chung Gun Lee, Sungho Won

Open access · greenAbstract read
In one paragraph

Article in Genes, brain, and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jinyeon JoDepartment of Public Health Sciences, Institute of Health & Environment, Seoul National University, Seoul, South Korea.ORCID 0000-0002-4192-1725
Youngkyu SongNGenebio Corps, Seoul, South Korea.
Dankyu YoonDivision of Endocrine and Kidney Disease Research, Department of Chronic Disease Convergence Research, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, South Korea.
Chung Gun LeeDepartment of Physical Education, College of Education, Seoul National University, Seoul, South Korea.ORCID 0000-0002-3314-3513
Sungho WonDepartment of Public Health Sciences, Institute of Health & Environment, Seoul National University, Seoul, South Korea.
Seoul National University · KRKorea Disease Control and Prevention Agency · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent genetic studies have identified physical activity (PA)-susceptible loci in European ancestry subjects; however, due to considerable genetic differences, these findings are not likely extendable to East Asian populations. Therefore, the present study aimed to identify significantly associated PA-susceptible loci using genome-wide association studies (GWASs) with East Asian (EAS) subjects and to generalize the findings to European (EUR) ancestries. The mRNA levels of genes located near the genome-wide significantly associated single-nucleotide polymorphisms (SNP) were compared under PA and control conditions. Rs74937256, located in ACSS3 (chromosome 12), which primarily functions in skeletal muscle tissues, was identified as a genome-wide significant variant (P = 6.06 × 10

Indexed as

ExerciseGenome-Wide Association StudyPolymorphism, Single NucleotideGenetic Predisposition to DiseaseHumansPhenotypeACSS3genome-wide association studyketone bodiesphysical activitiessingle-nucleotide polymorphism

Identifiers

PMID36510703
PMCPMC9994161
OpenAlexW4311288687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.