Evidence map›Paper›PMID 36510589›Full record

ArticleInfection and drug resistance2022

Risk Factors for Radiological Progression Within Admissive One Week in the Hospitalized COVID-19 Omicron Variant-Infected Patients.

Feng-Feng Zhu, Bin-Bin Gu, Yu-Jia Jin, Lin Yao, Lin Zhou, Di Zou, Jian Ding, Teng Zhou, Xing-Hua Shen, Cheng Chen

Abstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Feng-Feng Zhu *Intensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Bin-Bin Gu *Intensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.ORCID 0000-0003-3156-2535
Yu-Jia Jin *Department of Respiratory and Critical Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Lin YaoDepartment of Pulmonary, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Lin ZhouDepartment of Pulmonary, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Di ZouIntensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Jian DingIntensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Teng ZhouIntensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Xing-Hua ShenIntensive Care Unit, The Fifth People's Hospital of Suzhou, The Affiliated Infectious Disease Hospital of Soochow University, Suzhou, 215000, People's Republic of China.
Cheng ChenDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Recently, the SARS-CoV-2 Omicron variant was identified as responsible for a novel wave of COVID-19 worldwide. We perform a retrospective study to identify potential risk factors contributing to radiological progression in the COVID-19 patients due to the Omicron variant infection. These findings would provide guiding information for making clinical decisions that could improve the Omicron infection prognosis and reduce disease-related death. Methods: This is a retrospective cohort study from a single center in China. According to the radiological change within admissive one week, enrolled cases were divided into two groups: the progressive (1w-PD) and the stable or improved disease (1w-non-PD). Separate analyses were performed on patients stratified into subgroups using the Mann-Whitney Results: Both the 1w-non-PD and 1w-PD cohorts displayed comparable asymptomatic infection, have similar underlying disease, impairment in respiratory function, coagulation dysfunction, tissue injury, SARS-CoV-2 viral load, and disease severity. However, the 1w-PD cohort was more inclined to cluster in populations presented with age between 41 and 65, higher CURB-65 scores, undetectable SARS-CoV-2 IgG, and lung affection. Based on the multiple logistic regression analysis, complicated bilateral and ground-glass opacities (GGOs) like pneumonia at admission were independent risk factors to radiological progression within admissive one week. Conclusion: This study provided preliminary data regarding disease progression in Omicron-infected patients that indicated the development of pneumonia in the context of Omicron infection was worthy of potential risk factors.

Indexed as

COVID-19Omicronpneumoniaradiologyrisk

Identifiers

PMID36510589
PMCPMC9738098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.