ArticlePsychological medicine2023
Trajectories of depression and anxiety symptom severity during psychological therapy for common mental health problems.
Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Tracking Symptom Change Across Therapy Sessions in Virtual Reality Cognitive Behavioral Therapy Versus Cognitive Behavioral Therapy for Paranoid Ideation: A Secondary Analysis of a Randomized Controlled Trial.Schizophrenia bulletin · 2026Trial
- Learning How to Improve the Treatment of Persecutory Delusions: Using a Principal Trajectories Analysis to Examine Differential Effects of Two Psychological Interventions (Feeling Safe, Befriending) in Distinct Groups of Patients.Schizophrenia bulletin · 2026Trial
- A network-based analysis anticipates time to recovery from major depression revealing a plasticity by context interplay.Translational psychiatry · 2025Trial
- Long-term depressive symptom trajectories and related baseline characteristics in primary care patients: Analysis of the PsicAP clinical trial.European psychiatry : the journal of the Association of European Psychiatrists · 2024Trial
- Changes in Depressive Symptoms Following Mindfulness Training in Female Patients With Abdominal or Abdominopelvic Cancer: A Preliminary Non-Randomized Controlled Study.Psycho-oncology · 2026Article
- Psychotherapy is not just for Rich White People: Outcomes for Clients from Minoritized Backgrounds and in a Community Training Clinic.Journal of racial and ethnic health disparities · 2026Article
- Identifying distinct trajectories of change in anhedonia during psychological treatment for depression.Psychological medicine · 2026Article
- Factors associated with pain catastrophizing in patients with knee osteoarthritis: a cross-sectional study.Frontiers in public health · 2026Article
- Longitudinal trajectories of major depressive disorder provide further clinical perspectives for precision psychiatry.PCN reports : psychiatry and clinical neurosciences · 2025Review
- Anticipating depression trajectories by measuring plasticity and change through symptom network dynamics.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Depression care trajectories and sustainable return to work among long-term sick-listed workers: a register-based study (The Norwegian GP-DEP Study).BMC health services research · 2025Article
- Long-term depressive symptoms trajectories following CBT delivered in primary care compared to usual treatment.Psychological medicine · 2024Article
- Characterizing the post-traumatic growth trajectory in gastric cancer survivors: a population-based longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions.Frontiers in psychiatry · 2024Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThere is substantial variation in patient symptoms following psychological therapy for depression and anxiety. However, reliance on endpoint outcomes ignores additional interindividual variation during therapy. Knowing a patient's likely symptom trajectories could guide clinical decisions. We aimed to identify latent classes of patients with similar symptom trajectories over the course of psychological therapy and explore associations between baseline variables and trajectory class.
methodsPatients received high-intensity psychological treatment for common mental health problems at National Health Service Improving Access to Psychological Therapies services in South London (
resultsTrajectories of depression and anxiety symptoms were highly similar and best modelled by four classes. Three classes started with moderate-severe symptoms and showed (1) no change, (2) gradual improvement, and (3) fast improvement. A final class (4) showed initially mild symptoms and minimal improvement. Within the moderate-severe baseline symptom classes, patients in the two showing improvement as opposed to no change tended not to be prescribed psychotropic medication or report a disability and were in employment. Patients showing fast improvement additionally reported lower baseline functional impairment on average.
conclusionsMultiple trajectory classes of depression and anxiety symptoms were associated with baseline characteristics. Identifying the most likely trajectory for a patient at the start of treatment could inform decisions about the suitability and continuation of therapy, ultimately improving patient outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.