Evidence map›Paper›PMID 36510331›Full record

ArticleVeterinary research2022

Understanding the incidence and timing of rabies cases in domestic animals and wildlife in south-east Tanzania in the presence of widespread domestic dog vaccination campaigns.

Sarah Hayes, Kennedy Lushasi, Maganga Sambo, Joel Changalucha, Elaine A Ferguson, Lwitiko Sikana, Katie Hampson, Pierre Nouvellet, Christl A Donnelly

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. A Perspective of the Epidemiology of Rabies in South Africa, 1998-2019.Tropical medicine and infectious disease · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sarah HayesDepartment of Infectious Disease Epidemiology, Faculty of Medicine, School of Public Health, Imperial College London, London, UK. sarah.hayes@stats.ox.ac.uk.ORCID http://orcid.org/0000-0002-9976-6537
Kennedy LushasiIfakara Health Institute, Ifakara, Tanzania.
Maganga SamboIfakara Health Institute, Ifakara, Tanzania.
Joel ChangaluchaIfakara Health Institute, Ifakara, Tanzania.
Elaine A FergusonInstitute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, UK.
Lwitiko SikanaIfakara Health Institute, Ifakara, Tanzania.
Katie HampsonIfakara Health Institute, Ifakara, Tanzania.
Pierre NouvelletSchool of Life Sciences, University of Sussex, Sussex, UK.
Christl A DonnellyDepartment of Infectious Disease Epidemiology, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-0195-2463
Ifakara Health Institute · TZPublic Health England · GBUniversity of Glasgow · GBUniversity of Oxford · GBUniversity of Sussex · GB

Funding

Afrique One-ASPIRE DEL-15-008EPA EP-C-15-008Medical Research Council MR/R015600/1UK National Institute for Health and Care Research, Health Protection Research Unit in Emerging and Zoonotic Infections HPRU200907UK National Institute for Health and Care Research, Vaccine Efficacy Evaluation for Priority Emerging Diseases PR-OD-1017-20007Wellcome TrustWellcome Trust 095787/Z/11/ZWellcome Trust 107753/A/15/ZWellcome Trust 207569/Z/17/Z
6 · The paper itself

Abstract

The "Zero by 30" strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030 and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination has been implemented, it is important to assess the impact of this intervention. Additionally, understanding temporal and seasonal trends in the incidence of animal rabies cases may assist in optimizing such interventions. Data on the incidence of probable rabies cases in domestic and wild animals were collected between January 2011 and December 2018 in thirteen districts of south-east Tanzania where jackals comprise over 40% of reported rabies cases. Vaccination coverage was estimated over this period, as five domestic dog vaccination campaigns took place in all thirteen districts between 2011 and 2016. Negative binomial generalized linear models were used to explore the impact of domestic dog vaccination on the annual incidence of animal rabies cases, whilst generalized additive models were used to investigate the presence of temporal and/or seasonal trends. Increases in domestic dog vaccination coverage were significantly associated with a decreased incidence of rabies cases in both domestic dogs and jackals. A 35% increase in vaccination coverage was associated with a reduction in the incidence of probable dog rabies cases of between 78.0 and 85.5% (95% confidence intervals ranged from 61.2 to 92.2%) and a reduction in the incidence of probable jackal rabies cases of between 75.3 and 91.2% (95% confidence intervals ranged from 53.0 to 96.1%). A statistically significant common seasonality was identified in the monthly incidence of probable rabies cases in both domestic dogs and jackals with the highest incidence from February to August and lowest incidence from September to January. These results align with evidence supporting the use of domestic dog vaccination as part of control strategies aimed at reducing animal rabies cases in both domestic dogs and jackals in this region. The presence of a common seasonal trend requires further investigation but may have implications for the timing of future vaccination campaigns.

Indexed as

Dog DiseasesRabiesRabies VaccinesAnimalsAnimals, DomesticAnimals, WildDogsHumansIncidenceVaccinationRabies VaccinesjackalLyssavirusmulti-hostseasonalityZero by thirty

Identifiers

PMID36510331
PMCPMC9743725
OpenAlexW4311578411

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.