Evidence map›Paper›PMID 36510267›Full record

ArticleItalian journal of pediatrics2022

The value of QT interval in differentiating vasovagal syncope from epilepsy in children.

Xin Wang, Shuo Wang, Haihui Xiao, Runmei Zou, Hong Cai, Liqun Liu, Fang Li, Yuwen Wang, Yi Xu, Cheng Wang

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In one paragraph

Article in Italian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin WangDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Shuo WangDepartment of Neonatology , Xiangya Hospital, Central South University, Hunan, 410008, Changsha, China.
Haihui XiaoDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Runmei ZouDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Hong CaiDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Liqun LiuDepartment of Pediatric Neurology, Children's Medical Center, The Second Xiangya Hospital, Central South University, 410011, Changsha, China.
Fang LiDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Yuwen WangDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Yi XuDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China.
Cheng WangDepartment of Pediatric Cardiovasology, Children's Medical Center , The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Hunan, 410011, Changsha, China. wangcheng2nd@csu.edu.cn.ORCID http://orcid.org/0000-0002-7120-0654

Funding

Hunan Province Clinical Medical Technology Innovation Guidance Project 2020SK53405Peking University First Hospital 2022CR59
6 · The paper itself

Abstract

backgroundBoth vasovagal syncope (VVS) and epilepsy present with transient loss of consciousness and are often difficult to identify. Hence this study aimed to explore the value of QT interval in the differentiation of VVS and epilepsy in children.

methodsOne hundred thirteen children with unexplained transient loss of consciousness were selected. 56 children with VVS (VVS group), including 37 males and 19 females, the average age is 9.88 ± 2.55 years old. 57 children with epilepsy (epilepsy group), including 36 males and 21 females, the average age is 8.96 ± 2.67 years old. At the same time, the 60 healthy individuals (control group) were examined according to age and sex. The QT interval of 12-lead electrocardiogram in a basal state of three groups was measured and statistically analyzed by SPSS 24.0 software.

resultsCompared with the control group, (1) QTcmax, QTcmin and QTcd were significantly longer in VVS group (P < 0.05), QTmax and QTmin were significantly shorter in VVS group (P < 0.05), and there were no significant differences in QTd between the two groups (P > 0.05). (2) The QTmax and QTmin were significantly shorter in epilepsy group (P < 0.05), and there were no significant differences in QTd, QTcmax, QTcmin, QTcd between the two groups (P > 0.05). Compared with the epilepsy group, The QTcmax, QTcmin, QTcd were significantly longer in VVS group (P < 0.05), and there were no significant differences in QTd, QTmax, QTmin between the two groups (P > 0.05). When QTcmax > 479.84 ms, QTcmin > 398.90 ms and QTcd > 53.56 ms, the sensitivity and specificity of diagnosing VVS were 62.5% and 77.19%, 82.14% and 50.88%, 82.14% and 38.60% respectively.

conclusionQTcmax, QTcmin and QTcd have certain value in differentiating VVS from epilepsy in children.

Indexed as

EpilepsySyncope, VasovagalChildElectrocardiographyFemaleHumansMaleSensitivity and SpecificityChildrenDifferential diagnosisElectrocardiographyEpilepsyQT intervalVasovagal syncope

Identifiers

PMID36510267
PMCPMC9743691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.