Evidence map›Paper›PMID 36510026›Full record

ArticleChild psychiatry and human development2024

Specific Contamination Symptoms are Associated with Experiencing a Limited Response of Cognitive-Behavioral Therapy in Pediatric Patients with OCD.

Charlotte Steen Duholm, Sanne Jensen, Charlotte Ulrikka Rask, Per Hove Thomsen, Tord Ivarsson, Gudmundur Skarphedinsson, Nor Christian Torp, Bernhard Weidle, Judith Becker Nissen, Davíð R M A Højgaard

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Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Charlotte Steen DuholmDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark. chaduh@rm.dk.
Sanne JensenDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark.
Charlotte Ulrikka RaskDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark.
Per Hove ThomsenDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark.
Tord IvarssonInstitute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Gudmundur SkarphedinssonFaculty of Psychology, University of Iceland, Reykjavík, Iceland.
Nor Christian TorpDivision of Mental Health and Addiction, Vestre Viken Hospital, Drammen, Norway.
Bernhard WeidleRegional Centre for Child and Youth Mental Health and Child Welfare Central Norway, Norwegian University of Science and Technology, Trondheim, Norway.
Judith Becker NissenDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark.
Davíð R M A HøjgaardDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark.
Aarhus University · DKAarhus University Hospital · DKNorwegian University of Science and Technology · NOUniversity of Gothenburg · SEUniversity of Iceland · ISVestre Viken Hospital Trust · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent study identified three distinct treatment-response trajectories in pediatric OCD where higher levels of contamination symptoms predicted a limited response to cognitive-behavioral therapy (CBT). This study extends these findings by examining which specific symptoms characterize limited CBT response from baseline to 3-year follow-up, with an emphasis on contamination symptoms. The study sample comprised 269 pediatric patients with OCD, all receiving stepped-care treatment with manualized CBT. Differences in single item-reporting between the three trajectory groups were examined using linear mixed-effect modeling. Limited responders displayed a higher symptom load across all OCD symptom categories at 3-year follow-up, dominated by contamination symptoms. Five of these (obsessions about dirt and germs, about bodily fluids, about the feeling of contamination and compulsions regarding handwashing and showering) showed persistence from baseline to 3-year follow-up. The results indicate that presence of specific contamination symptoms may influence long-term symptom severity trajectories in young patients with OCD.

Indexed as

Cognitive Behavioral TherapyObsessive-Compulsive DisorderAdolescentChildFemaleFollow-Up StudiesHumansMaleSeverity of Illness IndexTreatment OutcomeChildren and adolescentsCognitive-behavioral therapyLongitudinal studyObsessive–compulsive disorderObsessive–compulsive symptoms

Identifiers

PMID36510026
OpenAlexW4311280841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.