Evidence map›Paper›PMID 36509640›Full record

ArticleVaccine2023

Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control study, Germany, June 2021 to January 2022.

Anna Stoliaroff-Pepin, Caroline Peine, Tim Herath, Johannes Lachmann, Delphine Perriat, Achim Dörre, Andreas Nitsche, Janine Michel, Marica Grossegesse, Natalie Hofmann and 21 more

Abstract readMulticenter Study
In one paragraph

Article in Vaccine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Anna Stoliaroff-PepinDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany. Electronic address: Stoliaroff-PepinA@rki.de.
Caroline PeineDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany. Electronic address: PeineC@rki.de.
Tim HerathDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.
Johannes LachmannDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.
Delphine PerriatDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.
Achim DörreDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Germany.
Andreas NitscheCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Janine MichelCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Marica GrossegesseCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Natalie HofmannCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Thomas RinnerCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Claudia KohlCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Annika BrinkmannCentre for Biological Threats and Special Pathogens, ZBS1 Highly Pathogenic Viruses, Robert Koch Institute, Germany.
Tanja MeyerCentre for Biological Threats and Special Pathogens, ZBS3 Biological Toxins, Robert Koch Institute, Germany.
Brigitte G DornerCentre for Biological Threats and Special Pathogens, ZBS3 Biological Toxins, Robert Koch Institute, Germany.
Daniel SternCentre for Biological Threats and Special Pathogens, ZBS3 Biological Toxins, Robert Koch Institute, Germany.
Fridolin TreindlCentre for Biological Threats and Special Pathogens, ZBS3 Biological Toxins, Robert Koch Institute, Germany.
Sascha HeinDivision Virology, Paul-Ehrlich-Institute, Germany.
Laura WerelDivision Virology, Paul-Ehrlich-Institute, Germany.
Eberhard HildtDivision Virology, Paul-Ehrlich-Institute, Germany.
Sven GläserKlinik für Innere Medizin - Pneumologie und Infektiologie, Vivantes Klinikum Neukölln und Spandau, Berlin, Germany.
Helmut SchühlenVivantes Netzwerk für Gesundheit GmbH, Direktorat Klinische Forschung & Akademische Lehre, Berlin, Germany.
Caroline IsnerKlinik für Innere Medizin - Infektiologie, Vivantes Auguste-Viktoria-Klinikum, Rubensstr. 125, 12157 Berlin, Germany.
Alexander PericKlinik für Pneumologie und Infektiologie, Vivantes Klinikum im Friedrichshain, Landsberger Allee 49, 10249 Berlin, Germany.
Ammar GhouziSchön Klinik Düsseldorf, Interdisziplinäre Notaufnahme, Am Heerdter Krankenhaus 2, 40549 Düsseldorf, Germany.
Annette ReichardtHelios Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Matthias JanneckKlinik für Kardiologie, Sektion Nephrologie, Albertinen Krankenhaus, Süntelstraße 11a, 22457 Hamburg, Germany.
Guntram LockKlinik für Innere Medizin, Albertinen Krankenhaus, Süntelstraße 11a, 22457 Hamburg, Germany.
Lars SchaadeCentre for Biological Threats and Special Pathogens, Robert Koch Institute, Germany.
Ole WichmannDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.
Thomas HarderDepartment for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We included 852 patients in a prospectively recruiting multicenter matched case-control study in Germany to assess vaccine effectiveness (VE) in preventing COVID-19-associated hospitalization during the Delta-variant dominance. The two-dose VE was 89 % (95 % CI 84-93 %) overall, 79 % in patients with more than two comorbidities and 77 % in adults aged 60-75 years. A third dose increased the VE to more than 93 % in all patient-subgroups.

Indexed as

COVID-19VaccinesAdultCase-Control StudiesGermanyHospitalizationHospitalsHumansVaccinesCase-control studyCOVID-19DeltaHospitalizationSARS-CoV-2Vaccine effectiveness

Identifiers

PMID36509640
PMCPMC9715487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.