Evidence map›Paper›PMID 36509511›Full record

ArticleHuman vaccines & immunotherapeutics2022

Effectiveness of varicella vaccination during an outbreak in a large one-dose-vaccinated population in Shanghai.

Mingzhu Lin, Qizhang Wang, Pengfei Deng, Shaotan Xiao, Yi Fei, Caoyi Xue

Open access · goldAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingzhu LinDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Qizhang WangDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Pengfei DengDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Shaotan XiaoDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Yi FeiDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Caoyi XueDepartment of Immunology, Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergency vaccination (EV) is used as effective postexposure prophylaxis (PEP) to control varicella outbreaks within 3-5 days. However, the advantages of a second dose of varicella vaccine (VarV) in students who had received one dose before an outbreak and the potential benefits of EV at more than 5 days after exposure have not been fully evaluated. This study evaluated the vaccine effectiveness (VE) of EV in preventing disease development during a varicella outbreak in Shanghai, China, in 2020. Questionnaires were used to obtain student demographic information, clinical manifestations, varicella history, vaccination status, and willingness to receive EV. The VE of EV was calculated as [1-relative risk (RR)] ×100%. Among the 1455 students included in this study, 31 cases were identified, resulting in an overall attack rate of 2.13%. There were 6 cases in unvaccinated students and 25 cases in one-dose-vaccinated students. A total of 788 students received one EV dose. The attack rates were 6.38% (6/94), 4.26% (19/446), 2.82% (2/71), and 0.56% (4/717) among unvaccinated students, students who received 1 dose of VarV, and students who received EV with the 1

Indexed as

ChickenpoxChickenpox VaccineAntigens, ViralChinaDisease OutbreaksHerpesvirus 3, HumanHumansStudentsVaccinationVaccines, AttenuatedAntigens, ViralChickenpox VaccineVaccines, Attenuatedemergency vaccinationOutbreakpostexposure prophylaxisvaccine effectivenessvaricella vaccine

Identifiers

PMID36509511
PMCPMC9766464
OpenAlexW4312137327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.