Evidence map›Paper›PMID 36508613›Full record

ArticleEuropean journal of preventive cardiology2023

Five-year changes in alcohol intake and risk of atrial fibrillation: a Danish cohort study.

Tanja Charlotte Frederiksen, Morten Krogh Christiansen, Emelia J Benjamin, Kim Overvad, Anja Olsen, Christina Catherine Dahm, Henrik Kjærulf Jensen

Open access · hybridAbstract read
In one paragraph

Article in European journal of preventive cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Dietary interventions in the management of atrial fibrillation.Frontiers in cardiovascular medicine · 2024
    Pooled it
  2. Article
  3. Alcohol and Atrial Fibrillation.Reviews in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tanja Charlotte FrederiksenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Blvd 99, 8200 Aarhus N, Denmark.ORCID 0000-0003-3338-9297
Morten Krogh ChristiansenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Blvd 99, 8200 Aarhus N, Denmark.ORCID 0000-0002-3894-888X
Emelia J BenjaminSections of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, 725 Albany Street, MA 02118, USA.ORCID 0000-0003-4076-2336
Kim OvervadResearch Unit for Epidemiology, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark.ORCID 0000-0001-6429-7921
Anja OlsenResearch Unit for Epidemiology, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark.ORCID 0000-0003-4788-503X
Christina Catherine DahmResearch Unit for Epidemiology, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark.ORCID 0000-0003-0481-2893
Henrik Kjærulf JensenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Blvd 99, 8200 Aarhus N, Denmark.ORCID 0000-0003-1802-4302
Aarhus University · DKAarhus University Hospital · DKBoston University · US

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
American Heart Association-American Stroke Association AHA_18SFRN34110082NHLBI NIH HHS R01HL092577
6 · The paper itself

Abstract

aimsAlcohol intake is a well-established risk factor for atrial fibrillation (AF). However, evidence on the effects of changes in alcohol intake to primary AF prevention is sparse. The aim of this study was to examine the association between 5-year changes in alcohol intake and the risk of incident AF. METHODS AND

resultsThis study was based on the Danish cohort study Diet, Cancer and Health. Lifestyle factors were assessed using questionnaires at a recruitment research examination and a second examination 5 years later. Diagnoses of AF and comorbidities were retrieved from the Danish National Patient Registry. 43 758 participants without prior AF were included. The median age was 61 (25th-75th percentile 58-66) years and 54% were female. Over a median follow-up time of 15.7 years, 5312 participants had incident AF (incidence rate 8.6/1000 person-years). Compared with stable intake, increases in alcohol intake to ≥21 drinks/week from ≤6.9 drinks/week (HR: 1.38, 95% CI: 1.09-1.72) or 14-20.9 drinks/week (HR: 1.27, 95% CI: 1.01-1.59) at baseline were associated with a higher risk of AF. In contrast, we did not observe a statistically significant association between reductions in alcohol intake and the risk of AF.

conclusionA 5-year increase in alcohol intake was associated with a greater risk of AF compared with a stable low/moderate intake.

Indexed as

Atrial FibrillationAlcohol DrinkingCohort StudiesDenmarkFemaleHumansIncidenceMaleMiddle AgedRisk FactorsAlcoholAtrial FibrillationcohortLifestylePrevention

Identifiers

PMID36508613
PMCPMC10442053
OpenAlexW4311290245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.