Evidence map›Paper›PMID 36508168›Full record

SynthesisAddiction (Abingdon, England)2023

Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study.

Antonio Verdejo-Garcia, Tara Rezapour, Emily Giddens, Arash Khojasteh Zonoozi, Parnian Rafei, Jamie Berry, Alfonso Caracuel, Marc L Copersino, Matt Field, Eric L Garland and 48 more

Abstract readSystematic ReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Addiction (Abingdon, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

58 authors.

Antonio Verdejo-GarciaSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia.ORCID 0000-0001-8874-9339
Tara RezapourDepartment of Cognitive Psychology, Institute for Cognitive Science Studies, Tehran, Iran.
Emily GiddensSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-5405-0164
Arash Khojasteh ZonooziIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Parnian RafeiIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Jamie BerryFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, Australia.
Alfonso CaracuelMind, Brain and Behavior Research Center, Universidad de Granada, Granada, Spain.ORCID 0000-0002-9738-8456
Marc L CopersinoMcLean Hospital and Harvard Medical School, Belmont, MA, USA.
Matt FieldDepartment of Psychology, University of Sheffield, Sheffield, UK.ORCID 0000-0002-7790-5559
Eric L GarlandCenter on Mindfulness and Integrative Health Intervention Development, University of Utah, Salt Lake City, UT, USA.
Valentina LorenzettiNeuroscience of Addiction and Mental Health Program, Healthy Brain and Mind Research Centre, School of Behavioral Sciences, Faculty of Health Sciences, Australian Catholic University, Melbourne, VIC, Australia.ORCID 0000-0002-5917-7068
Leandro Malloy-DinizMental Health Department, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Victoria ManningTurning Point Drug and Alcohol Centre and Monash Addiction Research Centre (MARC), Monash University, Melbourne, VIC, Australia.
Ely M MarceauSchool of Psychology and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia.
David L PenningtonDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Justin C StricklandDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1077-0394
Reinout WiersAddiction Development and Psychopathology (ADAPT) Laboratory, Department of Psychology, Centre for Urban Mental Health, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-4312-9766
Rahia FairheadSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia.
Alexandra AndersonSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-9976-0725
Morris BellDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Wouter J BoendermakerAddiction, Development, and Psychopathology (ADAPT) Laboratory, Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands.
Samantha BrooksResearch Centre for Brain and Behaviour, School of Psychology, Faculty of Health, Liverpool John Moores University, UK.
Raimondo BrunoSchool of Psychology, University of Tasmania, TAS, Hobart, Australia.
Salvatore CampanellaLaboratoire de Psychologie Médicale et d'Addictologie, ULB Neuroscience Institute (UNI), CHU Brugmann-Université Libre de Bruxelles, Bruxelles, Belgium.
Janna CousijnDepartment of Psychology, Education and Child Studies, Erasmus University Rotterdam, the Netherlands.ORCID 0000-0002-7699-2582
W Miles CoxSchool of Human and Behavioural Sciences, Bangor University, Bangor, UK.
Andrew C DeanDepartment of Psychiatry and Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, CA, USA.
Karen D ErscheDepartment of Psychiatry, University of Cambridge, Cambridge, UK.
Ingmar FrankenDepartment of Psychology, Education and Child Studies, Erasmus University Rotterdam, the Netherlands.ORCID 0000-0002-7853-2694
Brett FroeligerDepartment of Psychiatry and Psychological Sciences, University of Missouri, Columbia, MO, USA.
Pedro GamitoHEI-Lab, Lusófona University, Lisbon, Portugal.
Thomas E GladwinNo affiliation/independent researcher, London, UK.
Priscila D GoncalvesDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.ORCID 0000-0002-7684-0554
Katrijn HoubenFaculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Joanna JacobusDepartment of Psychiatry, University of California San Diego, CA, USA.ORCID 0000-0002-8587-3673
Andrew JonesDepartment of Psychology, University of Liverpool, UK.
Anne M KaagDepartment of Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, the Netherlands.ORCID 0000-0001-5696-5758
Johannes LindenmeyerSalus Klinik Lindow, Lindlow, Germany.
Elly McGrathFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Talia NardoSchool of Psychological Sciences, Macquarie University, NSW, Australia.
Jorge OliveiraHEI-Lab, Lusófona University, Lisbon, Portugal.
Charlotte R PenningtonSchool of Psychology, Aston University, Birmingham, UK.ORCID 0000-0002-5259-642X
Kelsey PerrykkadCognition and Philosophy Laboratory, Monash Centre for Consciousness and Contemplative Studies, Monash University, Melbourne, VIC, Australia.
Hugh PiercyMonash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia.
Claudia I RuppDepartment of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Clinics of Psychiatry I, Medical University Innsbruck, Innsbruck, Austria.
Mieke H J SchulteDepartment of Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, the Netherlands.
Lindsay M SquegliaDepartment of Psychiatry, Medical University of South Carolina, Charleston, SC, USA.
Petra StaigerSchool of Psychology, Deakin University, Melbourne, VIC, Australia.
Dan J SteinSAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
Jeff SteinCenter for Health Behaviors Research, Fralin Biomedical Research Institute at Virginial Tech, VA, USA.
Maria SteinDepartment for Clinical Psychology and Psychotherapy, University of Bern, Switzerland.ORCID 0000-0002-7458-1982
William W StoopsDepartment of Behavioral Science, University of Kentucky, Lexington, KY, USA.
Mary SweeneyBehavioral Pharmacology Research Unit, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Katie WitkiewitzDepartment of Psychology and Center on Alcohol, Substance Use and Addictions, University of New Mexico, NM, USA.ORCID 0000-0002-1086-3067
Steven P WoodsDepartment of Psychology, University of Houston, Houston, TX, USA.
Richard YiDepartment of Psychology, University of Kansas, Lawrence, KS, USA.
Min ZhaoShanghai Jiaotong University School of Medicine, Shanghai, China.
Hamed EkhtiariDepartment of Psychiatry, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-6902-8798

Funding

Substance Abuse Epidemiology Training Program (SAETP) at Columbia UniversityT32DA031099 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DEBORAH S HASIN, Silvia Saboia Martins · 2012 to 2026
$6.1M
Neuropsychobiology in Polysubstance Abusers during AbstinenceR01DA039903 · NIDA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI PENNINGTON, DAVID L · 2016 to 2021
$2.8M
Neural Links of Approach Bias Modification in Heavy Drinking VeteransIK2CX001510 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI PENNINGTON, DAVID L · 2017 to 2022
–
CSRD VA IK2 CX001510NIDA NIH HHS R01 DA039903NIDA NIH HHS T32 DA031099
6 · The paper itself

Abstract

aimsSubstance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing cognitive deficits in SUD. We aimed to reach consensus on recommendations for developing and applying these interventions. DESIGN, SETTING AND

participantsWe used a Delphi approach with two sequential phases: survey development and iterative surveying of experts. This was an on-line study. During survey development, we engaged a group of 15 experts from a working group of the International Society of Addiction Medicine (Steering Committee). During the surveying process, we engaged a larger pool of experts (n = 54) identified via recommendations from the Steering Committee and a systematic review. MEASUREMENTS: Survey with 67 items covering four key areas of intervention development: targets, intervention approaches, active ingredients and modes of delivery.

findingsAcross two iterative rounds (98% retention rate), the experts reached a consensus on 50 items including: (i) implicit biases, positive affect, arousal, executive functions and social processing as key targets of interventions; (ii) cognitive bias modification, contingency management, emotion regulation training and cognitive remediation as preferred approaches; (iii) practice, feedback, difficulty-titration, bias modification, goal-setting, strategy learning and meta-awareness as active ingredients; and (iv) both addiction treatment work-force and specialized neuropsychologists facilitating delivery, together with novel digital-based delivery modalities.

conclusionsExpert recommendations on cognitive training and remediation for substance use disorders highlight the relevance of targeting implicit biases, reward, emotion regulation and higher-order cognitive skills via well-validated intervention approaches qualified with mechanistic techniques and flexible delivery options.

Indexed as

Behavior, AddictiveSubstance-Related DisordersCognitive TrainingDelphi TechniqueHumansCognitive remediationcognitive trainingDelphi methodinterventionsneurosciencetreatment

Identifiers

PMID36508168
PMCPMC10073279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.