ArticleClinical medicine (London, England)2022
Public knowledge and information sources for clinical trials among adults in the USA: evidence from a Health Information National Trends Survey in 2020.
Article in Clinical medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 23 citations in OpenAlex.
- Factors Affecting Acceptance of Participating in Clinical Trials of New Drugs: A National Cross-Sectional Study.Journal of evidence-based medicine · 2026Article
- Feasibility and Methodological Reflections From the Co-Creation of a Randomized Controlled Trial (The Kid's Trial): Decentralized, Child-Led Citizen-Science Study.Journal of medical Internet research · 2026Article
- Ethical and Regulatory Awareness of Clinical Trials: A Nationwide Cross-Sectional Study from Poland.Therapeutic innovation & regulatory science · 2026Article
- Article
- Public Knowledge and Attitudes Towards Clinical Trial Participation: A Mixed-Method Study in Bagamoyo District, Tanzania.International journal of environmental research and public health · 2026Article
- Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation.Journal of clinical and translational science · 2026Article
- Mapping the path to diversity in clinical trials: a qualitative study of community member and stakeholder perspectives.BMC public health · 2025Article
- Knowledge of Clinical Trials Among US Cancer Survivors: Cross-Sectional Study of HINTS-SEER Data.JMIR cancer · 2025Article
- Do people prefer to take part in a clinical trial from home or come to site? A discrete choice experiment in type 2 diabetes mellitus.BMJ open · 2025Article
- Enhancing accessibility and impact of digitally enabled clinical trials: the WeShare engagement and equity toolkit.ESMO real world data and digital oncology · 2025Review
- Primer on Plain Language Summaries for Advanced Practice Providers With Published Examples and Practical Applications to Practice.Journal of the advanced practitioner in oncology · 2025Article
- Clinical trial knowledge, discussion, and participation among cancer survivors: A HINTS-SEER study.Patient education and counseling · 2025Article
- To increase trust in clinical research: Be worthy of trust and enhance the role of clinical research nurses.Journal of clinical and translational science · 2025Article
- Clinical trial knowledge among cancer survivors in the United States: the role of health information technology.Cancer causes & control : CCC · 2025Article
- COVID-19 clinical trial participation and awareness in Texas.Human vaccines & immunotherapeutics · 2024Article
- Knowledge and perception of a clinical trial among the participants: An experience from oral cholera vaccine study in Koshi Province, Nepal.Human vaccines & immunotherapeutics · 2024Article
- Using Short-Form Videos to Get Clinical Trial Newcomers to Sign Up: Message-Testing Experiment.Journal of medical Internet research · 2024Article
- A cross-sectional survey of clinical trials knowledge, participation, and perspectives in an underserved community of Washington, DC.Archives of dermatological research · 2024Article
- Racial and Ethnic Disparity in Approach for Pediatric Intensive Care Unit Research Participation.JAMA network open · 2024Article
- Recommending Clinical Trials for Online Patient Cases using Artificial Intelligence.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLack of clinical trial awareness has been identified as a barrier to clinical trial recruitment. Identifying factors associated with clinical trial knowledge could inform ongoing efforts to improve diversity in clinical trials.
methodsUsing data from the Health Information National Trends Survey, 2020, we examined the knowledge of clinical trials, associated characteristics, sources of clinical trial information and motives to participate in clinical trials among the general population in the USA.
resultsOf 3,772 US adults, 41.3% reported not knowing about clinical trials. Prevalence of having no knowledge of clinical trials was higher among Hispanic adults (51.8%) and non-Hispanic Black adults (41.8%) compared with non-Hispanic White adults (37.4%; p=0.013). Other significant predictors of knowledge about clinical trials included higher education, online health information-seeking behaviour and patient portal access. Most respondents (73.2%) reported that healthcare providers were the most trusted source of information. Helping other people (71.6%) was the primary motivation for clinical trial participation, followed by financial compensation (12.5%) and receiving better treatment (5.1%).
conclusionThere is a gap in knowledge about clinical trials among the US population. Development of multimodal approaches, including online and offline information broadcasting, is needed to improve knowledge and clinical trial recruitment in diverse populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.