Evidence map›Paper›PMID 36507808›Full record

ReviewClinical medicine (London, England)2022

Patent foramen ovale: diagnostic evaluation and the role of device closure.

Ahmed R Gonnah, Mahima S Bharadwaj, Hassan Nassar, Hesham K Abdelaziz, David Hesketh Roberts

Open access · diamondAbstract readReview
In one paragraph

Review in Clinical medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ahmed R GonnahUniversity of Liverpool School of Medicine, Liverpool, UK.
Mahima S BharadwajUniversity of Liverpool School of Medicine, Liverpool, UK m.s.bharadwaj@student.liverpool.ac.uk.
Hassan NassarUniversity of Liverpool School of Medicine, Liverpool, UK.
Hesham K AbdelazizBlackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK.
David Hesketh RobertsBlackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK and honorary senior clinical lecturer, University of Liverpool, Liverpool, UK.
University of Liverpool · GBBlackpool Teaching Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although seemingly benign, the presence of a patent foramen ovale (PFO) may play an important role in the pathophysiology of disease, specifically a paradoxical embolism leading to cryptogenic stroke. The European Society of Cardiology recently published guidelines detailing how PFOs are associated with paradoxical embolism and how they are diagnosed and managed. This review guides physicians in the diagnostic and referral process to a multidisciplinary team involved in PFO closure. It reviews the clinical trials comparing device closure with medical therapy and highlights the current NHS England commissioning process on PFO management. Finally, we give an overview of other conditions where PFO device closure may need to be considered.

Indexed as

Embolism, ParadoxicalForamen Ovale, PatentStrokeEnglandHumansSecondary PreventionTreatment Outcomecardiologycryptogenic strokemultidisciplinary teamparadoxical embolismpatent foramen ovale

Identifiers

PMID36507808
PMCPMC9595009
OpenAlexW4297914145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.