Evidence map›Paper›PMID 36507536›Full record

ArticleFrontiers in medicine2022

MicroRNA29B induces fetal hemoglobin

Qingqing Gu, Chithra D Palani, Alana Smith, Biaori Li, Ernestine Kubi Amos-Abanyie, Ugochi Ogu, Lu Lu, Betty S Pace, Athena Starlard-Davenport

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qingqing GuDepartment of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Chithra D PalaniDepartment of Pediatrics, Division of Hematology/Oncology, Augusta University, Augusta, GA, United States.
Alana SmithDepartment of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Biaori LiDepartment of Pediatrics, Division of Hematology/Oncology, Augusta University, Augusta, GA, United States.
Ernestine Kubi Amos-AbanyieDepartment of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Ugochi OguCenter for Sickle Cell Disease, Department of Medicine-Hematology, The University of Tennessee Health Science Center, Memphis, TN, United States.
Lu LuDepartment of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Betty S PaceDepartment of Pediatrics, Division of Hematology/Oncology, Augusta University, Augusta, GA, United States.
Athena Starlard-DavenportDepartment of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
University of Tennessee Health Science Center · USAugusta University · US

Funding

MicroRNA-based epigenetic approach to induce fetal hemoglobinR01HL144641 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI STARLARD-DAVENPORT, ATHENA · 2020 to 2022
$928k
NHLBI NIH HHS R01 HL144641
6 · The paper itself

Abstract

Introduction: Therapeutic strategies aimed at reactivating Materials and methods: Human KU812 were cultured and normal CD34 cells ( Results: Discussion: Our findings support the ability of MIR29B to induce HbF

Indexed as

fetal hemoglobin (HbF)HBGMIR29BMYBsickle cell

Identifiers

PMID36507536
PMCPMC9732025
OpenAlexW4310044130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.