Evidence map›Paper›PMID 36506609›Full record

ArticleMedicine and pharmacy reports2022

Quality of life, distress, anxiety and depression of ambulatory cancer patients receiving chemotherapy.

Aggeliki Papadopoulou, Ourania Govina, Ioanna Tsatsou, Marianna Mantzorou, Alexandra Mantoudi, Chrysoula Tsiou, Theodoula Adamakidou

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine and pharmacy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Aggeliki Papadopoulou417 NIMTS Army Veterans Hospital, Athens, Greece.
Ourania GovinaNursing Department, Postgraduate program "Neurological Disorders - Evidence Based Practice", University of West Attica, Athens, Greece.
Ioanna TsatsouOncology-Hematology Department, Hellenic Airforce General Hospital, Athens, Greece.
Marianna MantzorouNursing Department, Postgraduate program "Neurological Disorders - Evidence Based Practice", University of West Attica, Athens, Greece.
Alexandra MantoudiNursing Department, Postgraduate program "Neurological Disorders - Evidence Based Practice", University of West Attica, Athens, Greece.
Chrysoula TsiouNursing Department, Postgraduate program "Neurological Disorders - Evidence Based Practice", University of West Attica, Athens, Greece.
Theodoula AdamakidouNursing Department, Postgraduate program "Neurological Disorders - Evidence Based Practice", University of West Attica, Athens, Greece.
University of West Attica · GRHellenic Airforce General Hospital · GRNIMTS Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective and aim: Cancer and its treatment have substantial physical and psychological consequences that severely affect the patients' quality of life (QoL) and emotional status. This study aimed to investigate the relationship between distress, anxiety, depression, and QoL of ambulatory cancer patients undergoing chemotherapy. Methods: A descriptive, cross-sectional study of 150 cancer patients who were receiving chemotherapy in the outpatient unit of a central anticancer hospital in Athens. The data were collected through convenience sampling between November 2017 and January 2018, using a demographic and clinical characteristics questionnaire, the Distress Thermometer (DT) and Problem List (PL), the Hospital Anxiety and Depression Scale (HADS) and the European Organization for Research and Treatment for Cancer QoL assessment Questionnaire (EORTC QLQ-C30). Results: Variability characterized the sample's demographic and clinical characteristics. The majority of patients were women (64%), married (66%), high school graduates (43%), had breast cancer (35%), with a mean age of 60.07 ± 11.42. 83% reported anxiety, 75% reported fear, 51% nervousness and sadness, 34% depression and 84.7% fatigue. The DT was positively correlated with HADS (p<0.001) and with almost all EORTC QLQ-C30 functional subscales and symptoms (p<0.001). The HADS-Anxiety was significantly correlated with overall QoL and with almost all the EORTC QLQ-C30 functional scales and symptoms (p<0.001). HADS-Depression was significantly correlated with overall QoL and all the EORTC QLQ-C30 functional scales and symptoms (p<0.001). Women tended to have higher level of distress (p=0.003). There was a statistically significant relationship between educational level, the cognitive functioning scale (p=0.017) and financial difficulties (p=0.026). Conclusions: Ambulatory cancer patients undergoing chemotherapy are at risk of facing distress in all aspects of daily living, along with anxiety and depression, which decreases their QoL. Oncology nurses as members of multidisciplinary teams should assess the affected aspects of patients' QoL and appropriate interventions should be implemented at community level.

Indexed as

anxietycancer patientchemotherapydepressionquality of life

Identifiers

PMID36506609
PMCPMC9694751
OpenAlexW4306690359

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.