Evidence map›Paper›PMID 36506564›Full record

ArticleFrontiers in pharmacology2022

The association of gabapentin initiation and neurocognitive changes in older adults with normal cognition.

GYeon Oh, Daniela C Moga, David W Fardo, Erin L Abner

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06466421 (Clinical Study to Compare The Safety and Possible Efficacy of Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06466421 phase4completednot on this mapstarted 2024, after this paper: background citation

Clinical Study to Compare The Safety and Possible Efficacy of Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

TypeinterventionalSponsorTanta UniversityRan2024 to 2024Enrolled60ConditionsUremic Pruritus, Chronic Kidney Disease-associated Pruritus, Hemodialysis, End-stage Renal DiseaseArmsFexofenadine, Gabapentin
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. A Qualitative Study of the Effects of Opioids on Chronic Pain, Function, and Cognition in Community-Dwelling Older Adults.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. MEDICATION EXPOSURE AND NEURODEGENERATIVE DISEASE RISK ACROSS NATIONAL BIOBANKS.medRxiv : the preprint server for health sciences · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

GYeon OhSanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.
Daniela C MogaSanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.
David W FardoSanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.
Erin L AbnerSanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.
University of Kentucky · US

Funding

University of Kentucky Alzheimer's Disease Research CenterP30AG072946 · NIA · UNIVERSITY OF KENTUCKY · PI LINDA J VAN ELDIK · 2021 to 2026
$23.5M
Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)T32AG078110 · NIA · UNIVERSITY OF KENTUCKY · PI Michael Paul Murphy, LINDA J VAN ELDIK · 2022 to 2026
$2.3M
Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)T32AG057461 · NIA · UNIVERSITY OF KENTUCKY · PI MURPHY, MICHAEL PAUL, VAN ELDIK, LINDA J · 2017 to 2021
$2.1M
Genetic Architecture of Aging-Related TDP-43 and Mixed Pathology DementiaRF1AG082339 · NIA · UNIVERSITY OF KENTUCKY · PI FARDO, DAVID WILLIAM, NELSON, PETER T. · 2023 to 2023
$1.7M
NIA NIH HHS P30 AG072946NIA NIH HHS RF1 AG082339NIA NIH HHS T32 AG057461NIA NIH HHS T32 AG078110
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cognitive declinefunctional status changegabapentinmotor function changeNACC dataolder adults

Identifiers

PMID36506564
PMCPMC9732650
OpenAlexW4310044470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.