ArticleFrontiers in pharmacology2022
Discovery of the key active compounds in Citri Reticulatae Pericarpium (
Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Integrated Flavoromics and Metabolomics Reveal Aroma and Bioactive Characteristics of Six Mainstream Citri Reticulatae Pericarpium Cultivars.Foods (Basel, Switzerland) · 2026Article
- Multi-omics analyses reveal the effects of layerage and grafting on flavonoid synthesis and accumulation inHorticulture research · 2025Article
- Article
- Metabolic profile and bioactivity of the peel of Zhoupigan (Food chemistry: X · 2024Article
- A field survey on the dietary use of traditional Chinese medicine in selected regions with the Cantonese, Hakka, and Teochew populations in Guangdong province, China.Food science & nutrition · 2024Article
- Identification of South African Plant-Based Bioactive Compounds as Potential Inhibitors against the SARS-CoV-2 Receptor.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Neofunctionalization of anProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Insights into metabolic characteristics and biological activity changes in Zangju (Food chemistry: X · 2024Article
- Comparison of the volatile organic compounds inFrontiers in plant science · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Edible herbal medicines contain macro- and micronutrients and active metabolites that can take part in biochemical processes to help achieve or maintain a state of well-being. Citri Reticulatae Pericarpium (CRP) is an edible and medicinal herb used as a component of the traditional Chinese medicine (TCM) approach to treating COVID-19 in China. However, the material basis and related mechanistic research regarding this herb for the treatment of COVID-19 are still unclear. First, a wide-targeted UPLC-ESI-MS/MS-based comparative metabolomics analysis was conducted to screen for the active metabolites of CRP. Second, network pharmacology was used to uncover the initial linkages among these metabolites, their possible targets, and COVID-19. Each metabolite was then further studied
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