Evidence map›Paper›PMID 36506480›Full record

ArticleRSC advances2022

The concentration-dependent effect of hydrocortisone on the structure of model lung surfactant monolayer by using an

Mohammad Zohurul Islam, Sheikh I Hossain, E Deplazes, Zhen Luo, Suvash C Saha

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohammad Zohurul IslamSchool of Mechanical and Mechatronic Engineering, University of Technology Sydney 15 Broadway Ultimo 2007 NSW Australia Suvash.Saha@uts.edu.au.ORCID https://orcid.org/0000-0001-8196-8969
Sheikh I HossainSchool of Life Sciences, University of Technology Sydney 15 Broadway Ultimo 2007 NSW Australia Evelyne.Deplazes@uts.edu.au.
E DeplazesSchool of Life Sciences, University of Technology Sydney 15 Broadway Ultimo 2007 NSW Australia Evelyne.Deplazes@uts.edu.au.
Zhen LuoSchool of Mechanical and Mechatronic Engineering, University of Technology Sydney 15 Broadway Ultimo 2007 NSW Australia Suvash.Saha@uts.edu.au.
Suvash C SahaSchool of Mechanical and Mechatronic Engineering, University of Technology Sydney 15 Broadway Ultimo 2007 NSW Australia Suvash.Saha@uts.edu.au.ORCID https://orcid.org/0000-0002-9962-8919
University of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the adsorption mechanism of corticosteroids in the lung surfactant requires the knowledge of corticosteroid molecular interactions with lung surfactant monolayer (LSM). We employed coarse-grained molecular dynamics simulation to explore the action of hydrocortisone on an LSM comprised of a phospholipid, cholesterol and surfactant protein. The structural and dynamical morphology of the lung surfactant monolayer at different surface tensions were investigated to assess the monolayer compressibility. The simulations were also conducted at the two extreme ends of breathing cycles: exhalation (0 mN m

Identifiers

PMID36506480
PMCPMC9680622
OpenAlexW4311287754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.