Evidence map›Paper›PMID 36506366›Full record

ArticleHeliyon2022

Quantitative proteomics reveals potential anti-inflammatory protein targets of radial extracorporeal shock wave therapy in TNF-α-induced model of acute inflammation in primary human tenocytes.

Ruidong Ge, Qianzheng Zhu, Die Liu, Qi Zhang, Shan Jiang, Xueying Yu, Jun Shu, Fuqiang Gao, Jingwei Guo, Shengxuan Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ruidong GeDepartment of Rehabilitation Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Qianzheng ZhuDepartment of Orthopedics Trauma, China-Japan Friendship Hospital, Beijing, 100029, China.
Die LiuDepartment of Pediatrics, China-Japan Friendship Hospital, Beijing, 100029, China.
Qi ZhangDepartment of Pediatrics, China-Japan Friendship Hospital, Beijing, 100029, China.
Shan JiangDepartment of Rehabilitation Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Xueying YuClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China.
Jun ShuInstitute of Clinical Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Fuqiang GaoDepartment of Orthopedics, China-Japan Friendship Hospital, Beijing, 100029, China.
Jingwei GuoDepartment of Rehabilitation Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Shengxuan ChenDepartment of Rehabilitation Medicine, The Gulou Hospital of Traditional Chinese Medicine, Beijing, 100009, China.
Beiyao GaoDepartment of Rehabilitation Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
China-Japan Friendship Hospital · CNBeijing Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tendinopathy refers to a type of tendon disease with a multifactorial spectrum. Recent research has begun to reveal the effects of inflammation on the tendinopathic process, especially in the first stage of tendinopathy. Radial extracorporeal shock wave therapy (rESWT) has been successfully used to treat orthopedic diseases. However, the molecular mechanisms underlying the anti-inflammatory effects of rESWT on tumor necrosis factor-α treated tenocytes have not been fully elucidated. In this study, we applied total protein tandem mass tag-labeled quantitative proteomics with liquid chromatography-mass spectrometer/mass spectrometer technology to identify differentially expressed proteins (DEPs) among inflammatory tenocytes, rESWT inflammatory tenocytes, and controls using three biological replicates. Human tenocytes were used and they were cultured

Indexed as

InflammationProteomicShockwaveTendinopathyTenocyte

Identifiers

PMID36506366
PMCPMC9732318
OpenAlexW4311290424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.