Evidence map›Paper›PMID 36506312›Full record

ArticleFrontiers in genetics2022

A GHKNN model based on the physicochemical property extraction method to identify SNARE proteins.

Xingyue Gu, Yijie Ding, Pengfeng Xiao, Tao He

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xingyue GuState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.
Yijie DingYangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China, Quzhou, Zhejiang, China.
Pengfeng XiaoState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.
Tao HeBeidahuang Industry Group General Hospital, Harbin, China.
Quzhou University · CNSoutheast University · CNState Key Laboratory of Digital Medical Engineering

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a great deal of importance to SNARE proteins, and their absence from function can lead to a variety of diseases. The SNARE protein is known as a membrane fusion protein, and it is crucial for mediating vesicle fusion. The identification of SNARE proteins must therefore be conducted with an accurate method. Through extensive experiments, we have developed a model based on graph-regularized k-local hyperplane distance nearest neighbor model (GHKNN) binary classification. In this, the model uses the physicochemical property extraction method to extract protein sequence features and the SMOTE method to upsample protein sequence features. The combination achieves the most accurate performance for identifying all protein sequences. Finally, we compare the model based on GHKNN binary classification with other classifiers and measure them using four different metrics: SN, SP, ACC, and MCC. In experiments, the model performs significantly better than other classifiers.

Indexed as

GHKNNidentify protein sequencesphysicochemical property extraction methodSMOTESNARE proteins

Identifiers

PMID36506312
PMCPMC9727185
OpenAlexW4309706838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.