Evidence map›Paper›PMID 36506117›Full record

ArticleACS omega2022

Preparation, Characterization, and Evaluation of Curcumin-Graphene Oxide Complex-Loaded Liposomes against

Mahfoozur Rahman, Joina Gunjan Singh, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Majed Alrobaian, Jamshed Haneef, Md Abul Barkat, Waleed H Almalki, Mayank Handa, Rahul Shukla and 3 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Development, Characterization,Current medicinal chemistry · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Curcumin-Functionalized Graphene Oxide Strongly PreventsPharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Mahfoozur RahmanDepartment of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad211007, India.ORCID https://orcid.org/0000-0002-5616-4026
Joina Gunjan SinghDepartment of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad211007, India.
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Alkharj11942, Saudi Arabia.
Abdulmalik Saleh Alfawaz AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Alkharj11942, Saudi Arabia.
Majed AlrobaianDepartment of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif21944, Saudi Arabia.
Jamshed HaneefDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi110062, India.
Md Abul BarkatDepartment of Pharmaceutics, College of Pharmacy, University of Hafr Al Batin, Hafr Al Batin39524, Saudi Arabia.ORCID https://orcid.org/0000-0001-6009-5222
Waleed H AlmalkiDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah24382, Saudi Arabia.
Mayank HandaDepartment of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Raebareli, Lucknow, UP226002, India.ORCID https://orcid.org/0000-0001-9093-6432
Rahul ShuklaDepartment of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Raebareli, Lucknow, UP226002, India.ORCID https://orcid.org/0000-0002-4864-0133
Shehla Nasar Mir Najib UllahDepartment of Pharmacognosy, Faculty of Pharmacy, King Khalid University, Abha62529, Saudi Arabia.
Vikas KumarDepartment of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad211007, India.ORCID https://orcid.org/0000-0001-9984-0437
Sarwar BegDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi110062, India.ORCID https://orcid.org/0000-0002-3304-2712
Sam Higginbottom Institute of Agriculture · INJamia Hamdard · INNational Institute of Pharmaceutical Education and Research · INPrince Sattam Bin Abdulaziz University · SAKing Khalid University · SATaif University · SAUmm al-Qura University · SAUniversity of Hafr Al-Batin · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the development and characterization of curcumin with graphene oxide complex (CUR + GO) loaded into liposomes for treating skin disease. The developed complex was characterized by X-ray diffraction and showed a broad halo pattern, confirming the amorphous nature of the resulting complex. Furthermore, scanning electron microscopy revealed the irregular porous morphology of the complex-highlighting loss of the crystallinity and the emergence of the amorphous phase. Additionally, the liposomes showed long-term stability at 2-8 °C and 25 ± 2 °C/60 ± 5%RH with nonsignificant variations in the particle size, polydispersity index, and zeta potential. Overall, optical and high-resolution transmission electron microscopy images of liposomes showed a consistent shape, and no aggregation with uniform particle size distribution was observed. Furthermore, the cumulative drug release in the first 6 h was 71.24 and 64.24% for CUR-loaded liposomes and CUR-GO-loaded liposomes, respectively. The lower value of drug release might be attributed to the complex development. The drug release model found the first order with non-Fickian diffusion process, which is often observed at higher

Identifiers

PMID36506117
PMCPMC9730485
OpenAlexW4309425092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.