Evidence map›Paper›PMID 36506107›Full record

ArticleTherapeutic advances in medical oncology2022

Tumor glycolytic profiling through

Saulo Brito Silva, Carlos Wagner S Wanderley, José Flavio Gomes Marin, Mariana Petaccia de Macedo, Ellen Caroline Toledo do Nascimento, Fernanda Frozoni Antonacio, Caroline Sales Figueiredo, Mateus Trinconi Cunha, Fernando Q Cunha, Gilberto de Castro Junior

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in medical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. The role of baselineTherapeutic advances in medical oncology · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Saulo Brito SilvaHospital Sírio-Libanês, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-2095-4819
Carlos Wagner S WanderleyCenter for Research in Inflammatory Diseases (CRID) and Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.
José Flavio Gomes MarinHospital Sírio-Libanês, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-0678-8746
Mariana Petaccia de MacedoHospital Sírio-Libanês, Sao Paulo, Brazil.
Ellen Caroline Toledo do NascimentoHospital Sírio-Libanês, Sao Paulo, Brazil.
Fernanda Frozoni AntonacioHospital Sírio-Libanês, Sao Paulo, Brazil.
Caroline Sales FigueiredoHospital Sírio-Libanês, Sao Paulo, Brazil.
Mateus Trinconi CunhaInstituto do Câncer do Estado de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9101-8553
Fernando Q CunhaCenter for Research in Inflammatory Diseases (CRID) and Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0003-4755-1670
Gilberto de Castro JuniorCentro de Oncologia - Hospital Sírio Libanês, Rua D. Adma Jafet, 91, Térreo, Bela Vista, São Paulo 01308-050, Brazil.ORCID https://orcid.org/0000-0001-8765-3044
Hospital Sírio-Libanês · BRUniversidade de São Paulo · BRInstituto do Câncer do Estado de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A significant proportion of patients with non-small-cell lung cancer (NSCLC) do not respond to immune checkpoint inhibitors (ICIs). Since metabolic reprogramming with increased glycolysis is a hallmark of cancer and is involved in immune evasion, we used Methods: Results: In all, 98 patients were included. Lower baseline Conclusions: Glycolytic metabolic profiles established through baseline

Indexed as

18F-FDG PET/CTbiomarkersglycolysisimmunotherapynon-small-cell lung cancerWarburg effect

Identifiers

PMID36506107
PMCPMC9730014
OpenAlexW4311284686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.