Evidence map›Paper›PMID 36506067›Full record

ArticleFrontiers in endocrinology2022

A novel nomogram containing efficacy indicators to predict axillary pathologic complete response after neoadjuvant systemic therapy in breast cancer.

Wenjie Shi, Xiaofeng Huang, Ye Wang, Xinyu Wan, Jinzhi He, Yinggang Xu, Weiwei Zhang, Rui Chen, Lu Xu, Xiaoming Zha and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Wenjie ShiDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaofeng HuangDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ye WangDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xinyu WanDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jinzhi HeDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yinggang XuDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Weiwei ZhangDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Rui ChenDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lu XuDepartment of Clinical Nutrition, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaoming ZhaDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jue WangDepartment of Breast Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neoadjuvant systemic therapy (NST) could make some clinically node-positive (cN+) breast cancer patients achieve axillary pathologic complete response (pCR). This study aimed to identify the patients who are likely to achieve axillary pCR and help surgeons make surgical decisions on the axilla. Methods: The cN+ breast cancer patients who received NST from 2015 to 2021 at The First Affiliated Hospital of Nanjing Medical University were enrolled. Univariate and multivariate logistic regression analyses were performed, and a nomogram was constructed based on the results of multivariate logistic regression analysis to predict the probability of axillary pCR and validated. Results: The axillary pCR was achieved in 208 (38.7%) patients. Patients who had a higher radiological response rate of breast tumor ( Conclusion: A nomogram was constructed to predict the axillary pCR of cN+ patients receiving NST based on baseline and efficacy indicators to assist surgeons in making surgical decisions on the axilla.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyAxillaFemaleHumansLymphatic MetastasisNomogramsBreast cancerefficacy indicatorsneoadjuvant systemic therapynomogrampathologic complete response

Identifiers

PMID36506067
PMCPMC9732273
OpenAlexW4310040210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.