Evidence map›Paper›PMID 36506042›Full record

ArticleFrontiers in endocrinology2022

A nomogram model based on clinical markers for predicting malignancy of ovarian tumors.

Bingsi Gao, Xingping Zhao, Pan Gu, Dan Sun, Xinyi Liu, Waixing Li, Aiqian Zhang, Enuo Peng, Dabao Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Bingsi GaoDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xingping ZhaoDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Pan GuDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Dan SunDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xinyi LiuDepartment of Obstetrics and Gynecology, Hunan Provincial Maternal and Child Health Hospital, Changsha, Hunan, China.
Waixing LiDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Aiqian ZhangDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Enuo PengDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Dabao XuDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Central South University · CNHunan Provincial Maternal and Child Health Hospital · CNObstetrics and Gynecology Hospital of Fudan University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to build a nomogram based on clinical markers for predicting the malignancy of ovarian tumors (OTs). Method: A total of 1,268 patients diagnosed with OTs that were surgically removed between October 2017 and May 2019 were enrolled. Clinical markers such as post-menopausal status, body mass index (BMI), serum human epididymis protein 4 (HE4) value, cancer antigen 125 (CA125) value, Risk of Ovarian Malignancy Algorithm (ROMA) index, course of disease, patient-generated subjective global assessment (PG-SGA) score, ascites, and locations and features of masses were recorded and analyzed ( Result: The significant variables included post-menopausal status, BMI, HE4 value, CA125 value, ROMA index, course of disease, PG-SGA score, ascites, and features and locations of masses ( Conclusion: We successfully tailored a nomogram model based on selected clinical markers which showed superior prognostic predictive accuracy compared with the use of the CA125, HE4, or ROMA index (that combines both HE and CA125 values) for predicting the malignancy of OT patients.

Indexed as

Ovarian NeoplasmsAlgorithmsBiomarkersBody Mass IndexFemaleHumansNomogramsBiomarkersclinical markersmalignantovarian cancerovarian tumorsprognostic nomogram model

Identifiers

PMID36506042
PMCPMC9729545
OpenAlexW4309842443

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.